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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PARD6A
All Species:
22.12
Human Site:
S295
Identified Species:
44.24
UniProt:
Q9NPB6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NPB6
NP_001032358.1
346
37388
S295
E
N
R
Q
P
P
S
S
N
G
L
S
Q
G
P
Chimpanzee
Pan troglodytes
XP_511037
346
37345
S295
E
N
R
Q
P
P
S
S
N
G
L
S
Q
G
P
Rhesus Macaque
Macaca mulatta
XP_001092684
345
37352
S295
E
N
R
Q
P
P
S
S
N
G
L
S
Q
G
P
Dog
Lupus familis
XP_546876
347
37080
S296
E
N
R
Q
P
P
C
S
N
G
L
S
Q
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z101
346
37315
S295
E
N
R
H
P
P
C
S
N
G
L
S
Q
G
P
Rat
Rattus norvegicus
Q6B4M5
346
37380
S295
E
N
R
H
P
P
C
S
N
G
L
S
Q
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516968
349
37646
F294
N
H
P
P
P
R
Y
F
S
P
C
L
N
G
A
Chicken
Gallus gallus
XP_425103
358
38540
E292
Y
S
T
A
E
S
D
E
E
G
D
L
V
I
E
Frog
Xenopus laevis
NP_001081992
377
41958
S296
Y
L
P
E
D
A
E
S
D
E
E
D
I
I
I
Zebra Danio
Brachydanio rerio
NP_001093521
385
41919
N291
Q
N
T
S
Q
Y
S
N
S
N
S
V
A
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9NAN2
309
34201
Q261
L
S
R
G
P
S
Q
Q
G
T
P
N
A
S
E
Sea Urchin
Strong. purpuratus
XP_792763
376
41713
P302
V
Q
D
H
S
E
K
P
A
E
T
G
G
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.5
78.9
N.A.
93
92.4
N.A.
77.3
63.4
49.3
51.4
N.A.
N.A.
N.A.
45.6
44.6
Protein Similarity:
100
99.7
99.1
80.9
N.A.
94.5
94.2
N.A.
83.6
77
66
65.7
N.A.
N.A.
N.A.
60.6
58.7
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
13.3
6.6
6.6
13.3
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
26.6
13.3
20
33.3
N.A.
N.A.
N.A.
26.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
9
0
0
9
0
0
0
17
0
9
% A
% Cys:
0
0
0
0
0
0
25
0
0
0
9
0
0
0
0
% C
% Asp:
0
0
9
0
9
0
9
0
9
0
9
9
0
9
0
% D
% Glu:
50
0
0
9
9
9
9
9
9
17
9
0
0
9
17
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
9
59
0
9
9
59
17
% G
% His:
0
9
0
25
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
9
17
9
% I
% Lys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% K
% Leu:
9
9
0
0
0
0
0
0
0
0
50
17
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
59
0
0
0
0
0
9
50
9
0
9
9
0
0
% N
% Pro:
0
0
17
9
67
50
0
9
0
9
9
0
0
0
50
% P
% Gln:
9
9
0
34
9
0
9
9
0
0
0
0
50
0
0
% Q
% Arg:
0
0
59
0
0
9
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
17
0
9
9
17
34
59
17
0
9
50
0
9
0
% S
% Thr:
0
0
17
0
0
0
0
0
0
9
9
0
0
0
0
% T
% Val:
9
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
17
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _