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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PARD6A All Species: 40.91
Human Site: S178 Identified Species: 81.82
UniProt: Q9NPB6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NPB6 NP_001032358.1 346 37388 S178 F Y I R D G M S V R V A P Q G
Chimpanzee Pan troglodytes XP_511037 346 37345 S178 F Y I R D G M S V R V A P Q G
Rhesus Macaque Macaca mulatta XP_001092684 345 37352 S178 F Y I R D G M S V R V A P Q G
Dog Lupus familis XP_546876 347 37080 S179 F Y I R D G M S V R V A P Q G
Cat Felis silvestris
Mouse Mus musculus Q9Z101 346 37315 S178 F Y I R D G M S V R V A P Q G
Rat Rattus norvegicus Q6B4M5 346 37380 S178 F Y I R D G M S V R V A P Q G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516968 349 37646 S177 F Y I R D G V S V R V A P Q G
Chicken Gallus gallus XP_425103 358 38540 S174 F Y I R D G V S V V R V A P Q
Frog Xenopus laevis NP_001081992 377 41958 S179 F Y I R D G S S V R M T P H G
Zebra Danio Brachydanio rerio NP_001093521 385 41919 S174 F Y I R D G V S V R V T S H G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9NAN2 309 34201 D146 R Q V S A I I D V D I V P E A
Sea Urchin Strong. purpuratus XP_792763 376 41713 S185 F Y I R D G T S M R V T P H G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.5 78.9 N.A. 93 92.4 N.A. 77.3 63.4 49.3 51.4 N.A. N.A. N.A. 45.6 44.6
Protein Similarity: 100 99.7 99.1 80.9 N.A. 94.5 94.2 N.A. 83.6 77 66 65.7 N.A. N.A. N.A. 60.6 58.7
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 93.3 53.3 73.3 73.3 N.A. N.A. N.A. 13.3 73.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 60 80 80 N.A. N.A. N.A. 40 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 0 0 0 0 0 0 59 9 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 92 0 0 9 0 9 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % E
% Phe: 92 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 92 0 0 0 0 0 0 0 0 84 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 25 0 % H
% Ile: 0 0 92 0 0 9 9 0 0 0 9 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 50 0 9 0 9 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 84 9 0 % P
% Gln: 0 9 0 0 0 0 0 0 0 0 0 0 0 59 9 % Q
% Arg: 9 0 0 92 0 0 0 0 0 84 9 0 0 0 0 % R
% Ser: 0 0 0 9 0 0 9 92 0 0 0 0 9 0 0 % S
% Thr: 0 0 0 0 0 0 9 0 0 0 0 25 0 0 0 % T
% Val: 0 0 9 0 0 0 25 0 92 9 75 17 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 92 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _