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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLXIPL
All Species:
16.06
Human Site:
T653
Identified Species:
27.18
UniProt:
Q9NP71
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP71
NP_116569.1
852
93073
T653
K
T
E
N
R
R
I
T
H
I
S
A
E
Q
K
Chimpanzee
Pan troglodytes
XP_509441
819
90122
K623
A
L
K
N
R
Q
M
K
H
I
S
A
E
Q
K
Rhesus Macaque
Macaca mulatta
XP_001115131
390
43669
Q216
G
G
W
P
P
P
E
Q
W
C
K
Q
L
F
S
Dog
Lupus familis
XP_546925
857
93734
T658
K
T
E
N
R
R
I
T
H
I
S
A
E
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q99MZ3
864
94857
T665
K
M
E
N
R
R
I
T
H
I
S
A
E
Q
K
Rat
Rattus norvegicus
Q6AXT8
471
49872
P297
P
A
P
V
V
H
P
P
T
S
G
V
H
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001104311
895
97370
T697
K
M
E
S
R
R
I
T
H
I
S
A
E
Q
K
Frog
Xenopus laevis
NP_001084764
548
60887
S374
V
R
R
E
R
A
A
S
V
G
S
L
S
T
S
Zebra Danio
Brachydanio rerio
XP_001338503
817
90800
N628
N
S
Q
S
R
R
V
N
H
I
S
A
E
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724328
836
92381
G632
R
D
T
Q
R
R
A
G
H
I
H
A
E
Q
K
Honey Bee
Apis mellifera
XP_394429
1014
115124
G814
Y
K
E
Q
R
R
V
G
H
I
H
A
E
Q
K
Nematode Worm
Caenorhab. elegans
P41846
1009
112841
T715
Q
H
P
P
K
I
I
T
P
P
S
A
S
S
K
Sea Urchin
Strong. purpuratus
XP_788672
1338
148936
V1115
N
A
T
T
A
S
P
V
I
T
I
A
T
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVN1
1266
139556
P885
S
L
F
S
A
S
A
P
E
Q
A
G
K
S
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.6
42.9
87.7
N.A.
81.4
20.8
N.A.
N.A.
51.4
30.9
39.4
N.A.
20
29.5
25.5
21.1
Protein Similarity:
100
55.4
43.9
91.4
N.A.
85.7
29.3
N.A.
N.A.
60.7
41.6
53.5
N.A.
36.5
44.9
41.3
33.5
P-Site Identity:
100
60
0
100
N.A.
93.3
0
N.A.
N.A.
86.6
13.3
60
N.A.
53.3
60
33.3
6.6
P-Site Similarity:
100
80
0
100
N.A.
93.3
0
N.A.
N.A.
93.3
20
86.6
N.A.
60
66.6
46.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
0
0
15
8
22
0
0
0
8
72
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
36
8
0
0
8
0
8
0
0
0
58
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
8
8
0
0
0
0
0
15
0
8
8
8
0
0
0
% G
% His:
0
8
0
0
0
8
0
0
58
0
15
0
8
0
0
% H
% Ile:
0
0
0
0
0
8
36
0
8
58
8
0
0
0
0
% I
% Lys:
29
8
8
0
8
0
0
8
0
0
8
0
8
0
65
% K
% Leu:
0
15
0
0
0
0
0
0
0
0
0
8
8
0
0
% L
% Met:
0
15
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
0
29
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
8
0
15
15
8
8
15
15
8
8
0
0
0
8
8
% P
% Gln:
8
0
8
15
0
8
0
8
0
8
0
8
0
58
0
% Q
% Arg:
8
8
8
0
65
50
0
0
0
0
0
0
0
0
8
% R
% Ser:
8
8
0
22
0
15
0
8
0
8
58
0
15
22
15
% S
% Thr:
0
15
15
8
0
0
0
36
8
8
0
0
8
8
8
% T
% Val:
8
0
0
8
8
0
15
8
8
0
0
8
0
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _