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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLXIPL
All Species:
25.15
Human Site:
S688
Identified Species:
42.56
UniProt:
Q9NP71
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP71
NP_116569.1
852
93073
S688
A
Q
P
S
L
K
V
S
K
A
T
T
L
Q
K
Chimpanzee
Pan troglodytes
XP_509441
819
90122
T658
K
L
T
S
H
A
I
T
L
Q
K
T
V
E
Y
Rhesus Macaque
Macaca mulatta
XP_001115131
390
43669
D251
D
L
N
C
F
L
S
D
I
S
D
T
L
F
T
Dog
Lupus familis
XP_546925
857
93734
S693
A
Q
P
S
L
K
V
S
K
A
T
T
L
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q99MZ3
864
94857
S700
A
Q
P
S
L
K
V
S
K
A
T
T
L
Q
K
Rat
Rattus norvegicus
Q6AXT8
471
49872
P332
P
A
P
G
V
H
P
P
A
P
G
V
H
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001104311
895
97370
S732
A
Q
P
S
I
K
V
S
K
A
T
T
L
Q
K
Frog
Xenopus laevis
NP_001084764
548
60887
S409
V
F
P
L
F
P
N
S
A
A
S
P
N
V
P
Zebra Danio
Brachydanio rerio
XP_001338503
817
90800
Y663
T
L
Q
K
T
V
D
Y
I
G
K
L
Q
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724328
836
92381
S667
L
N
P
N
A
K
L
S
K
A
A
M
L
Q
K
Honey Bee
Apis mellifera
XP_394429
1014
115124
S849
Q
N
P
N
T
K
M
S
K
A
A
M
L
Q
K
Nematode Worm
Caenorhab. elegans
P41846
1009
112841
A750
N
L
L
N
G
K
M
A
V
K
V
E
E
K
S
Sea Urchin
Strong. purpuratus
XP_788672
1338
148936
T1150
L
P
A
F
S
L
S
T
T
P
I
N
I
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVN1
1266
139556
S920
Y
N
C
E
I
M
L
S
K
V
K
V
P
L
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.6
42.9
87.7
N.A.
81.4
20.8
N.A.
N.A.
51.4
30.9
39.4
N.A.
20
29.5
25.5
21.1
Protein Similarity:
100
55.4
43.9
91.4
N.A.
85.7
29.3
N.A.
N.A.
60.7
41.6
53.5
N.A.
36.5
44.9
41.3
33.5
P-Site Identity:
100
13.3
13.3
100
N.A.
100
6.6
N.A.
N.A.
93.3
20
0
N.A.
53.3
53.3
6.6
0
P-Site Similarity:
100
40
20
100
N.A.
100
13.3
N.A.
N.A.
100
26.6
6.6
N.A.
66.6
66.6
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
29
8
8
0
8
8
0
8
15
50
15
0
0
0
0
% A
% Cys:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
8
8
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
0
8
8
8
8
% E
% Phe:
0
8
0
8
15
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
8
8
0
0
0
0
8
8
0
0
0
0
% G
% His:
0
0
0
0
8
8
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
15
0
8
0
15
0
8
0
8
0
0
% I
% Lys:
8
0
0
8
0
50
0
0
50
8
22
0
0
8
43
% K
% Leu:
15
29
8
8
22
15
15
0
8
0
0
8
50
15
0
% L
% Met:
0
0
0
0
0
8
15
0
0
0
0
15
0
0
0
% M
% Asn:
8
22
8
22
0
0
8
0
0
0
0
8
8
0
0
% N
% Pro:
8
8
58
0
0
8
8
8
0
15
0
8
8
8
22
% P
% Gln:
8
29
8
0
0
0
0
0
0
8
0
0
8
43
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
36
8
0
15
58
0
8
8
0
0
8
8
% S
% Thr:
8
0
8
0
15
0
0
15
8
0
29
43
0
0
8
% T
% Val:
8
0
0
0
8
8
29
0
8
8
8
15
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _