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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCB6
All Species:
10.61
Human Site:
S470
Identified Species:
19.44
UniProt:
Q9NP58
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP58
NP_005680.1
842
93886
S470
V
K
Y
Y
N
A
E
S
Y
E
V
E
R
Y
R
Chimpanzee
Pan troglodytes
XP_001161097
843
94009
S470
V
K
Y
Y
N
A
E
S
Y
E
V
E
R
Y
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536073
1099
120564
G729
V
K
Y
Y
N
A
E
G
Y
E
V
N
C
Y
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9DC29
842
93752
G470
V
K
Y
Y
G
A
E
G
Y
E
V
D
R
Y
R
Rat
Rattus norvegicus
O70595
836
93286
G470
V
K
Y
Y
N
A
E
G
Y
E
L
E
R
Y
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001139165
800
90747
S462
V
K
Y
Y
N
A
E
S
Y
E
V
G
R
F
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650503
866
97867
H455
V
K
Y
Y
G
A
E
H
Y
E
V
D
C
Y
R
Honey Bee
Apis mellifera
XP_001122583
748
85114
T411
I
V
C
S
G
L
L
T
G
S
L
L
C
L
H
Nematode Worm
Caenorhab. elegans
NP_001022812
801
90557
Y442
F
K
N
A
I
E
S
Y
Q
V
T
E
W
K
T
Sea Urchin
Strong. purpuratus
XP_001181861
832
94582
A456
V
K
Y
Y
N
N
E
A
F
E
V
N
I
Y
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVM1
728
80402
S391
A
F
L
N
F
G
Q
S
I
I
F
S
T
A
L
Baker's Yeast
Sacchar. cerevisiae
P40416
690
77504
A353
Q
N
L
I
F
T
T
A
L
T
A
M
M
Y
M
Red Bread Mold
Neurospora crassa
Q7RX59
716
78739
A379
Y
M
G
A
H
G
V
A
T
G
Q
L
T
V
G
Conservation
Percent
Protein Identity:
100
99.5
N.A.
67.7
N.A.
88.9
87.4
N.A.
N.A.
N.A.
N.A.
61.7
N.A.
49.5
50
42.5
51.3
Protein Similarity:
100
99.6
N.A.
71.5
N.A.
93.4
92.9
N.A.
N.A.
N.A.
N.A.
74.9
N.A.
64.7
65.9
59.1
66.2
P-Site Identity:
100
100
N.A.
80
N.A.
80
86.6
N.A.
N.A.
N.A.
N.A.
80
N.A.
73.3
0
13.3
60
P-Site Similarity:
100
100
N.A.
80
N.A.
86.6
93.3
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
80
20
13.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.3
33
35.2
Protein Similarity:
N.A.
N.A.
N.A.
52.4
49.5
51.5
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
16
0
54
0
24
0
0
8
0
0
8
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
24
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
8
% D
% Glu:
0
0
0
0
0
8
62
0
0
62
0
31
0
0
8
% E
% Phe:
8
8
0
0
16
0
0
0
8
0
8
0
0
8
0
% F
% Gly:
0
0
8
0
24
16
0
24
8
8
0
8
0
0
8
% G
% His:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
8
% H
% Ile:
8
0
0
8
8
0
0
0
8
8
0
0
8
0
0
% I
% Lys:
0
70
0
0
0
0
0
0
0
0
0
0
0
8
0
% K
% Leu:
0
0
16
0
0
8
8
0
8
0
16
16
0
8
8
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
8
8
0
8
% M
% Asn:
0
8
8
8
47
8
0
0
0
0
0
16
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
8
0
8
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
39
0
47
% R
% Ser:
0
0
0
8
0
0
8
31
0
8
0
8
0
0
0
% S
% Thr:
0
0
0
0
0
8
8
8
8
8
8
0
16
0
8
% T
% Val:
62
8
0
0
0
0
8
0
0
8
54
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
8
0
62
62
0
0
0
8
54
0
0
0
0
62
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _