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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCB6 All Species: 20
Human Site: S237 Identified Species: 36.67
UniProt: Q9NP58 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NP58 NP_005680.1 842 93886 S237 V R S A A Q Q S T W R D F G R
Chimpanzee Pan troglodytes XP_001161097 843 94009 S237 V R S A A Q Q S T W R D F G R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536073 1099 120564 S496 T T E A P P R S T W R D L G R
Cat Felis silvestris
Mouse Mus musculus Q9DC29 842 93752 S237 G R S T D R R S T W R D L G R
Rat Rattus norvegicus O70595 836 93286 S237 G R S T D P R S T W R D L G R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001139165 800 90747 S229 G N S D E D Q S T W K D F G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650503 866 97867 S223 Q G N V Q T G S A F R N G W R
Honey Bee Apis mellifera XP_001122583 748 85114 D192 I Y N K K I V D S I S E A P E
Nematode Worm Caenorhab. elegans NP_001022812 801 90557 L223 W P T K S I S L Q L R V V F C
Sea Urchin Strong. purpuratus XP_001181861 832 94582 S225 L S G P E N A S T W A N A M L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LVM1 728 80402 A172 K L A V D W L A S A T G T G A
Baker's Yeast Sacchar. cerevisiae P40416 690 77504 Q134 Q V P F F F K Q T I D S M N I
Red Bread Mold Neurospora crassa Q7RX59 716 78739 G160 N I D F S T T G G S V T A V A
Conservation
Percent
Protein Identity: 100 99.5 N.A. 67.7 N.A. 88.9 87.4 N.A. N.A. N.A. N.A. 61.7 N.A. 49.5 50 42.5 51.3
Protein Similarity: 100 99.6 N.A. 71.5 N.A. 93.4 92.9 N.A. N.A. N.A. N.A. 74.9 N.A. 64.7 65.9 59.1 66.2
P-Site Identity: 100 100 N.A. 53.3 N.A. 60 60 N.A. N.A. N.A. N.A. 53.3 N.A. 20 0 6.6 20
P-Site Similarity: 100 100 N.A. 60 N.A. 73.3 66.6 N.A. N.A. N.A. N.A. 66.6 N.A. 40 26.6 20 33.3
Percent
Protein Identity: N.A. N.A. N.A. 36.3 33 35.2
Protein Similarity: N.A. N.A. N.A. 52.4 49.5 51.5
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 0
P-Site Similarity: N.A. N.A. N.A. 26.6 13.3 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 24 16 0 8 8 8 8 8 0 24 0 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 8 8 24 8 0 8 0 0 8 47 0 0 0 % D
% Glu: 0 0 8 0 16 0 0 0 0 0 0 8 0 0 8 % E
% Phe: 0 0 0 16 8 8 0 0 0 8 0 0 24 8 0 % F
% Gly: 24 8 8 0 0 0 8 8 8 0 0 8 8 54 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 8 0 0 0 16 0 0 0 16 0 0 0 0 8 % I
% Lys: 8 0 0 16 8 0 8 0 0 0 8 0 0 0 8 % K
% Leu: 8 8 0 0 0 0 8 8 0 8 0 0 24 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % M
% Asn: 8 8 16 0 0 8 0 0 0 0 0 16 0 8 0 % N
% Pro: 0 8 8 8 8 16 0 0 0 0 0 0 0 8 0 % P
% Gln: 16 0 0 0 8 16 24 8 8 0 0 0 0 0 0 % Q
% Arg: 0 31 0 0 0 8 24 0 0 0 54 0 0 0 47 % R
% Ser: 0 8 39 0 16 0 8 62 16 8 8 8 0 0 0 % S
% Thr: 8 8 8 16 0 16 8 0 62 0 8 8 8 0 0 % T
% Val: 16 8 0 16 0 0 8 0 0 0 8 8 8 8 0 % V
% Trp: 8 0 0 0 0 8 0 0 0 54 0 0 0 8 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _