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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRPC7
All Species:
35.76
Human Site:
Y720
Identified Species:
78.67
UniProt:
Q9HCX4
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCX4
NP_065122.1
862
99562
Y720
P
S
P
K
S
F
Y
Y
L
I
M
R
I
K
M
Chimpanzee
Pan troglodytes
XP_001169715
862
99535
Y720
P
S
P
K
S
F
Y
Y
L
I
M
R
I
K
M
Rhesus Macaque
Macaca mulatta
XP_001111979
862
99426
Y720
P
S
P
K
S
F
Y
Y
L
I
M
R
I
K
M
Dog
Lupus familis
XP_538642
1041
119299
Y899
P
S
P
K
S
F
Y
Y
L
I
M
R
I
K
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVC5
862
99456
Y720
P
S
P
K
S
F
Y
Y
L
I
M
R
I
K
M
Rat
Rattus norvegicus
Q9JMI9
836
95664
Y706
P
S
P
K
S
F
V
Y
F
I
M
R
I
T
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513859
925
106258
Y795
P
S
P
K
S
F
V
Y
L
I
M
R
I
V
N
Chicken
Gallus gallus
XP_425214
858
98958
Y725
P
S
P
K
S
F
Y
Y
L
I
L
R
I
K
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_695955
829
94737
S707
L
S
Y
F
D
E
G
S
T
L
P
A
P
F
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJJ7
1128
127091
Y700
P
T
P
K
S
I
W
Y
A
I
K
W
M
R
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34586
1027
118084
Y708
V
T
P
K
S
L
I
Y
V
M
N
C
L
F
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99
81.8
N.A.
98.1
79
N.A.
74.5
93.5
N.A.
80.7
N.A.
25.7
N.A.
33.2
N.A.
Protein Similarity:
100
99.8
99.5
82.4
N.A.
99.4
87.3
N.A.
83.5
96
N.A.
89
N.A.
43.5
N.A.
52.5
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
73.3
N.A.
80
93.3
N.A.
6.6
N.A.
40
N.A.
26.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
73.3
N.A.
80
100
N.A.
13.3
N.A.
66.6
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
73
0
0
10
0
0
0
0
19
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
10
0
0
82
0
0
73
0
0
% I
% Lys:
0
0
0
91
0
0
0
0
0
0
10
0
0
55
0
% K
% Leu:
10
0
0
0
0
10
0
0
64
10
10
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
64
0
10
0
55
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
37
% N
% Pro:
82
0
91
0
0
0
0
0
0
0
10
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
73
0
10
10
% R
% Ser:
0
82
0
0
91
0
0
10
0
0
0
0
0
0
0
% S
% Thr:
0
19
0
0
0
0
0
0
10
0
0
0
0
10
0
% T
% Val:
10
0
0
0
0
0
19
0
10
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
10
0
0
0
55
91
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _