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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRPC7 All Species: 30.61
Human Site: S39 Identified Species: 67.33
UniProt: Q9HCX4 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HCX4 NP_065122.1 862 99562 S39 M F N E K G T S L T P E E E R
Chimpanzee Pan troglodytes XP_001169715 862 99535 S39 M F N E K G T S L T P E E E R
Rhesus Macaque Macaca mulatta XP_001111979 862 99426 S39 M F N E K G T S L T A E E E R
Dog Lupus familis XP_538642 1041 119299 S218 M F N E K G T S L T P E E E R
Cat Felis silvestris
Mouse Mus musculus Q9WVC5 862 99456 S39 M F N E K G T S L T P E E E R
Rat Rattus norvegicus Q9JMI9 836 95664 N39 L D A A E Y G N I P V V R K M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513859 925 106258 S112 M F N D R G T S L T A E E E R
Chicken Gallus gallus XP_425214 858 98958 S44 M F N E K G T S L T A E E E R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_695955 829 94737 S43 M F S E R G T S L T E E E E R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VJJ7 1128 127091 Q41 A G T R R M L Q K A Q D T E Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34586 1027 118084 M45 V H I R T N D M I S P E E R R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99 81.8 N.A. 98.1 79 N.A. 74.5 93.5 N.A. 80.7 N.A. 25.7 N.A. 33.2 N.A.
Protein Similarity: 100 99.8 99.5 82.4 N.A. 99.4 87.3 N.A. 83.5 96 N.A. 89 N.A. 43.5 N.A. 52.5 N.A.
P-Site Identity: 100 100 93.3 100 N.A. 100 0 N.A. 80 93.3 N.A. 80 N.A. 6.6 N.A. 26.6 N.A.
P-Site Similarity: 100 100 93.3 100 N.A. 100 33.3 N.A. 93.3 93.3 N.A. 93.3 N.A. 20 N.A. 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 10 0 0 0 0 0 10 28 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 10 0 0 10 0 0 0 0 10 0 0 0 % D
% Glu: 0 0 0 64 10 0 0 0 0 0 10 82 82 82 0 % E
% Phe: 0 73 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 0 73 10 0 0 0 0 0 0 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 19 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 55 0 0 0 10 0 0 0 0 10 0 % K
% Leu: 10 0 0 0 0 0 10 0 73 0 0 0 0 0 0 % L
% Met: 73 0 0 0 0 10 0 10 0 0 0 0 0 0 10 % M
% Asn: 0 0 64 0 0 10 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 10 46 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 10 0 0 10 0 0 0 0 % Q
% Arg: 0 0 0 19 28 0 0 0 0 0 0 0 10 10 82 % R
% Ser: 0 0 10 0 0 0 0 73 0 10 0 0 0 0 0 % S
% Thr: 0 0 10 0 10 0 73 0 0 73 0 0 10 0 0 % T
% Val: 10 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _