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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CELSR2
All Species:
14.85
Human Site:
S2733
Identified Species:
40.83
UniProt:
Q9HCU4
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCU4
NP_001399.1
2923
317453
S2733
L
E
D
D
Q
S
G
S
Y
A
S
T
H
S
S
Chimpanzee
Pan troglodytes
XP_001146508
2916
314007
S2709
L
S
I
P
S
S
E
S
E
D
N
G
R
T
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537042
2926
317616
S2736
L
E
D
D
Q
S
G
S
Y
A
S
T
H
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0M0
2920
317575
S2734
L
E
D
D
Q
S
G
S
Y
A
S
T
H
S
S
Rat
Rattus norvegicus
Q9QYP2
2144
233463
S1967
A
S
T
H
S
S
D
S
E
E
E
E
E
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414354
3758
413869
P3528
V
I
F
R
T
Q
L
P
H
Y
S
I
L
G
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001074046
2941
323651
S2765
N
S
S
H
L
S
L
S
E
Q
N
T
L
F
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V5N8
3579
397124
T3213
R
T
A
R
S
S
G
T
H
R
S
T
A
V
S
Honey Bee
Apis mellifera
XP_624236
3166
348062
D2888
E
G
G
G
R
S
L
D
L
A
S
S
H
S
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.1
N.A.
96.7
N.A.
94.4
70.5
N.A.
N.A.
43.9
N.A.
63.1
N.A.
33.3
37.9
N.A.
N.A.
Protein Similarity:
100
62.6
N.A.
98.1
N.A.
96.2
71.7
N.A.
N.A.
55.9
N.A.
76.4
N.A.
48.3
53.8
N.A.
N.A.
P-Site Identity:
100
20
N.A.
100
N.A.
100
13.3
N.A.
N.A.
6.6
N.A.
20
N.A.
33.3
40
N.A.
N.A.
P-Site Similarity:
100
33.3
N.A.
100
N.A.
100
20
N.A.
N.A.
20
N.A.
26.6
N.A.
46.6
53.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
12
0
0
0
0
0
0
45
0
0
12
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
34
34
0
0
12
12
0
12
0
0
0
0
0
% D
% Glu:
12
34
0
0
0
0
12
0
34
12
12
12
12
12
0
% E
% Phe:
0
0
12
0
0
0
0
0
0
0
0
0
0
12
0
% F
% Gly:
0
12
12
12
0
0
45
0
0
0
0
12
0
12
0
% G
% His:
0
0
0
23
0
0
0
0
23
0
0
0
45
0
0
% H
% Ile:
0
12
12
0
0
0
0
0
0
0
0
12
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% K
% Leu:
45
0
0
0
12
0
34
0
12
0
0
0
23
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
0
0
0
0
23
0
0
0
0
% N
% Pro:
0
0
0
12
0
0
0
12
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
34
12
0
0
0
12
0
0
0
0
0
% Q
% Arg:
12
0
0
23
12
0
0
0
0
12
0
0
12
0
23
% R
% Ser:
0
34
12
0
34
89
0
67
0
0
67
12
0
45
56
% S
% Thr:
0
12
12
0
12
0
0
12
0
0
0
56
0
12
0
% T
% Val:
12
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
34
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _