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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGF22
All Species:
27.88
Human Site:
S161
Identified Species:
68.15
UniProt:
Q9HCT0
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCT0
NP_065688.1
170
19663
S161
R
T
R
R
Y
H
L
S
A
H
F
L
P
V
L
Chimpanzee
Pan troglodytes
XP_524019
195
22108
S186
R
T
R
R
Y
H
L
S
A
H
F
L
P
V
L
Rhesus Macaque
Macaca mulatta
XP_001091268
170
19708
S161
R
T
R
R
Y
H
L
S
A
H
F
L
P
V
L
Dog
Lupus familis
XP_855276
224
24759
S214
K
T
R
R
K
N
T
S
A
H
F
L
P
M
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9ESS2
162
18908
S152
R
T
R
R
H
Q
L
S
T
H
F
L
P
V
L
Rat
Rattus norvegicus
P70492
215
24011
S205
K
T
R
R
K
N
T
S
A
H
F
L
P
M
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518820
193
21965
S184
K
T
R
R
Q
H
L
S
T
H
F
L
P
I
L
Chicken
Gallus gallus
P48801
220
25031
S177
K
T
R
R
T
Q
K
S
S
L
F
L
P
R
V
Frog
Xenopus laevis
Q91875
209
23644
F185
R
T
K
R
H
Q
K
F
T
H
F
L
P
R
P
Zebra Danio
Brachydanio rerio
P48802
256
28905
A200
K
T
R
S
T
D
K
A
S
L
F
L
P
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.5
94.7
40.1
N.A.
81.7
41.8
N.A.
42.4
35.4
35.4
32.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
67.6
95.8
58.4
N.A.
86.4
61.4
N.A.
53.8
51.3
51.2
40.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
60
N.A.
80
60
N.A.
73.3
46.6
46.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
86.6
66.6
60
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
50
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
100
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
20
40
0
0
0
80
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
50
0
10
0
20
0
30
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
50
0
0
20
0
100
0
0
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% M
% Asn:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
10
% P
% Gln:
0
0
0
0
10
30
0
0
0
0
0
0
0
0
0
% Q
% Arg:
50
0
90
90
0
0
0
0
0
0
0
0
0
30
0
% R
% Ser:
0
0
0
10
0
0
0
80
20
0
0
0
0
0
0
% S
% Thr:
0
100
0
0
20
0
20
0
30
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
40
40
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
30
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _