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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GBA2
All Species:
24.24
Human Site:
S741
Identified Species:
76.19
UniProt:
Q9HCG7
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCG7
NP_065995.1
927
104649
S741
R
Y
Y
N
Y
D
S
S
S
R
P
Q
S
R
S
Chimpanzee
Pan troglodytes
XP_520565
927
104692
S741
R
Y
Y
N
Y
D
S
S
S
R
P
Q
S
R
S
Rhesus Macaque
Macaca mulatta
XP_001084705
927
104548
S741
R
Y
Y
N
Y
D
S
S
S
Q
P
Q
S
R
S
Dog
Lupus familis
XP_531991
1136
126441
S952
R
Y
Y
N
Y
D
C
S
P
Q
P
Q
S
C
S
Cat
Felis silvestris
Mouse
Mus musculus
Q69ZF3
918
103275
S732
R
Y
Y
N
Y
D
S
S
S
H
P
Q
S
R
S
Rat
Rattus norvegicus
Q5M868
912
102729
S732
R
Y
Y
N
Y
D
S
S
S
Q
P
Q
S
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KT91
948
108273
K776
G
K
R
S
L
E
E
K
L
W
N
G
S
Y
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002328722
922
102994
S716
S
Y
F
N
Y
D
D
S
N
G
R
N
S
P
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.1
72.8
N.A.
86.7
87.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
38.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
98.2
76.8
N.A.
92
91.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
52.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
73.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
93.3
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
37.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
54.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
60
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
13
0
0
0
0
0
0
13
0
% C
% Asp:
0
0
0
0
0
88
13
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
13
13
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
0
0
0
0
0
0
0
0
13
0
13
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
13
0
0
0
0
0
13
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
13
0
0
0
13
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
88
0
0
0
0
13
0
13
13
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
13
0
75
0
0
13
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
38
0
75
0
0
0
% Q
% Arg:
75
0
13
0
0
0
0
0
0
25
13
0
0
63
0
% R
% Ser:
13
0
0
13
0
0
63
88
63
0
0
0
100
0
88
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% W
% Tyr:
0
88
75
0
88
0
0
0
0
0
0
0
0
13
13
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _