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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GBA2
All Species:
22.73
Human Site:
S579
Identified Species:
71.43
UniProt:
Q9HCG7
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCG7
NP_065995.1
927
104649
S579
T
R
R
R
Y
L
M
S
G
V
M
A
P
V
K
Chimpanzee
Pan troglodytes
XP_520565
927
104692
S579
T
R
R
R
Y
L
M
S
G
V
M
A
P
V
K
Rhesus Macaque
Macaca mulatta
XP_001084705
927
104548
S579
T
R
R
Q
Y
L
M
S
G
V
M
A
P
V
K
Dog
Lupus familis
XP_531991
1136
126441
S790
T
R
R
Q
Y
L
M
S
G
V
M
A
P
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q69ZF3
918
103275
S570
T
R
R
R
Y
L
M
S
G
V
V
A
P
V
K
Rat
Rattus norvegicus
Q5M868
912
102729
S570
T
R
R
R
Y
L
M
S
G
V
V
A
P
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KT91
948
108273
R569
Y
D
G
K
V
M
P
R
K
V
K
N
C
V
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002328722
922
102994
D557
S
K
M
H
L
L
L
D
G
Q
C
V
T
R
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.1
72.8
N.A.
86.7
87.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
38.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
98.2
76.8
N.A.
92
91.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
52.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
37.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
54.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
75
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
13
0
13
0
0
% C
% Asp:
0
13
0
0
0
0
0
13
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
13
0
0
0
0
0
88
0
0
0
0
0
0
% G
% His:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
13
0
13
0
0
0
0
13
0
13
0
0
0
88
% K
% Leu:
0
0
0
0
13
88
13
0
0
0
0
0
0
0
0
% L
% Met:
0
0
13
0
0
13
75
0
0
0
50
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% N
% Pro:
0
0
0
0
0
0
13
0
0
0
0
0
75
0
13
% P
% Gln:
0
0
0
25
0
0
0
0
0
13
0
0
0
0
0
% Q
% Arg:
0
75
75
50
0
0
0
13
0
0
0
0
0
13
0
% R
% Ser:
13
0
0
0
0
0
0
75
0
0
0
0
0
0
0
% S
% Thr:
75
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% T
% Val:
0
0
0
0
13
0
0
0
0
88
25
13
0
88
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
0
0
0
75
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _