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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL14
All Species:
13.64
Human Site:
T105
Identified Species:
60
UniProt:
Q9HCE5
Number Species:
5
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCE5
NP_066012.1
456
52150
T105
E
I
Y
K
D
S
S
T
F
L
K
G
T
Q
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q3UIK4
456
52104
T105
E
I
Y
K
D
S
S
T
F
L
K
G
T
Q
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZK35
459
52502
T105
E
I
Y
K
D
S
S
T
F
L
K
G
T
Q
S
Frog
Xenopus laevis
Q6NU56
456
51949
T105
E
I
Y
K
D
S
S
T
F
L
K
G
T
Q
S
Zebra Danio
Brachydanio rerio
Q6NZ22
455
52160
F105
V
Y
K
D
S
S
T
F
L
K
G
T
Q
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VLP7
397
44832
H94
P
H
N
D
Y
C
Q
H
F
V
D
T
G
Q
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
98.6
N.A.
N.A.
N.A.
94.1
85.3
83.3
N.A.
59.4
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
99.3
N.A.
N.A.
N.A.
98
91.8
90.7
N.A.
69.5
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
N.A.
N.A.
100
100
6.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
N.A.
N.A.
100
100
13.3
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
34
67
0
0
0
0
0
17
0
0
0
0
% D
% Glu:
67
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
17
84
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
17
67
17
0
0
% G
% His:
0
17
0
0
0
0
0
17
0
0
0
0
0
0
0
% H
% Ile:
0
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
17
67
0
0
0
0
0
17
67
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
17
67
0
0
0
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
17
0
0
0
0
0
17
84
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% R
% Ser:
0
0
0
0
17
84
67
0
0
0
0
0
0
17
67
% S
% Thr:
0
0
0
0
0
0
17
67
0
0
0
34
67
0
0
% T
% Val:
17
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
17
67
0
17
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _