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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE28
All Species:
3.33
Human Site:
T533
Identified Species:
6.67
UniProt:
Q9HCC9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCC9
NP_066023.1
887
96490
T533
S
L
D
S
A
V
A
T
Q
E
A
A
S
E
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116192
715
75453
A376
S
A
V
A
T
Q
E
A
A
S
E
P
V
A
E
Dog
Lupus familis
XP_545920
606
64606
C267
W
A
L
G
P
N
S
C
S
C
L
D
S
Q
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZPK7
905
99769
H535
A
A
Q
E
A
P
G
H
G
T
S
P
L
E
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521608
312
34972
Chicken
Gallus gallus
XP_420832
912
101903
C547
T
P
E
A
A
I
N
C
V
P
G
S
A
N
P
Frog
Xenopus laevis
NP_001087164
538
61276
P199
I
S
G
L
L
I
Y
P
D
G
P
L
N
L
Q
Zebra Danio
Brachydanio rerio
A0JMD2
969
106945
N591
C
A
G
G
C
V
D
N
H
E
D
A
M
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VB70
989
108781
S564
E
P
T
T
I
K
A
S
E
E
H
M
Q
Q
P
Honey Bee
Apis mellifera
XP_397433
1240
139257
P672
N
A
Q
E
K
N
I
P
R
I
S
S
N
F
D
Nematode Worm
Caenorhab. elegans
Q9TZD0
661
74507
R322
E
K
A
K
N
N
Q
R
V
W
M
C
D
M
P
Sea Urchin
Strong. purpuratus
XP_785516
997
110048
S613
T
T
G
T
V
G
N
S
T
Q
R
I
P
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
57.9
45.4
N.A.
81.7
N.A.
N.A.
30.5
69.1
32.1
55.1
N.A.
31
32.1
30.4
36.7
Protein Similarity:
100
N.A.
62.9
51
N.A.
86.5
N.A.
N.A.
32.8
78.9
43.6
64.4
N.A.
44.9
45
44
50.7
P-Site Identity:
100
N.A.
6.6
13.3
N.A.
20
N.A.
N.A.
0
13.3
0
33.3
N.A.
20
0
6.6
0
P-Site Similarity:
100
N.A.
13.3
26.6
N.A.
33.3
N.A.
N.A.
0
53.3
13.3
33.3
N.A.
46.6
33.3
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
42
9
17
25
0
17
9
9
0
9
17
9
9
0
% A
% Cys:
9
0
0
0
9
0
0
17
0
9
0
9
0
0
0
% C
% Asp:
0
0
9
0
0
0
9
0
9
0
9
9
9
0
9
% D
% Glu:
17
0
9
17
0
0
9
0
9
25
9
0
0
25
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
25
17
0
9
9
0
9
9
9
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
9
9
0
9
0
0
0
0
% H
% Ile:
9
0
0
0
9
17
9
0
0
9
0
9
0
0
0
% I
% Lys:
0
9
0
9
9
9
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
9
9
9
0
0
0
0
0
9
9
9
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
9
9
9
0
% M
% Asn:
9
0
0
0
9
25
17
9
0
0
0
0
17
9
0
% N
% Pro:
0
17
0
0
9
9
0
17
0
9
9
17
9
0
59
% P
% Gln:
0
0
17
0
0
9
9
0
9
9
0
0
9
17
9
% Q
% Arg:
0
0
0
0
0
0
0
9
9
0
9
0
0
0
0
% R
% Ser:
17
9
0
9
0
0
9
17
9
9
17
17
17
0
0
% S
% Thr:
17
9
9
17
9
0
0
9
9
9
0
0
0
0
0
% T
% Val:
0
0
9
0
9
17
0
0
17
0
0
0
9
0
0
% V
% Trp:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _