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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPON1
All Species:
20.61
Human Site:
S186
Identified Species:
41.21
UniProt:
Q9HCB6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCB6
NP_006099.2
807
90973
S186
K
K
L
C
E
Q
D
S
T
F
D
G
V
T
D
Chimpanzee
Pan troglodytes
XP_508295
807
90900
S186
K
K
L
C
E
Q
D
S
T
F
D
G
V
T
D
Rhesus Macaque
Macaca mulatta
XP_001093336
807
90914
S186
K
K
L
C
E
Q
D
S
T
F
D
G
V
T
D
Dog
Lupus familis
XP_534067
807
90758
S186
K
K
L
C
E
Q
D
S
M
F
D
G
V
T
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCC9
807
90803
P186
K
K
L
C
E
Q
D
P
T
L
D
G
V
T
D
Rat
Rattus norvegicus
P35446
807
90755
P186
K
K
L
C
E
Q
D
P
T
L
D
G
V
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9W770
802
90491
S181
K
R
I
C
E
Q
D
S
A
S
E
G
V
T
D
Frog
Xenopus laevis
P35447
803
90684
L182
K
R
M
C
E
L
D
L
T
L
E
G
G
N
E
Zebra Danio
Brachydanio rerio
NP_571590
808
90627
S186
K
R
M
C
E
K
E
S
L
Y
G
E
T
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610757
873
98263
G246
L
R
E
V
A
E
H
G
S
T
R
T
L
E
S
Honey Bee
Apis mellifera
XP_396636
845
96276
E181
I
C
Q
D
S
K
A
E
A
D
N
Q
G
P
V
Nematode Worm
Caenorhab. elegans
NP_495473
819
92401
I180
C
I
Q
K
G
T
Q
I
L
K
P
V
D
D
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.3
98.2
N.A.
96.2
96.7
N.A.
N.A.
87.4
82.1
76.6
N.A.
31.5
33.4
29.7
N.A.
Protein Similarity:
100
100
99.6
99.3
N.A.
98.5
98.8
N.A.
N.A.
92.8
89.7
87.7
N.A.
48.3
50.6
47.1
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
66.6
40
40
N.A.
0
0
0
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
86.6
66.6
73.3
N.A.
26.6
13.3
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
9
0
17
0
0
0
0
0
0
% A
% Cys:
9
9
0
75
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
67
0
0
9
50
0
9
9
67
% D
% Glu:
0
0
9
0
75
9
9
9
0
0
17
9
0
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
34
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
0
0
9
0
0
9
67
17
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
9
9
9
0
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
75
50
0
9
0
17
0
0
0
9
0
0
0
0
0
% K
% Leu:
9
0
50
0
0
9
0
9
17
25
0
0
9
0
0
% L
% Met:
0
0
17
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
9
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
17
0
0
9
0
0
9
9
% P
% Gln:
0
0
17
0
0
59
9
0
0
0
0
9
0
0
0
% Q
% Arg:
0
34
0
0
0
0
0
0
0
0
9
0
0
0
0
% R
% Ser:
0
0
0
0
9
0
0
50
9
9
0
0
0
0
9
% S
% Thr:
0
0
0
0
0
9
0
0
50
9
0
9
9
67
0
% T
% Val:
0
0
0
9
0
0
0
0
0
0
0
9
59
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _