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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK6
All Species:
21.21
Human Site:
T35
Identified Species:
51.85
UniProt:
Q9HC98
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HC98
NP_001138473.1
313
35714
T35
D
P
Q
R
H
P
N
T
L
S
F
R
C
S
L
Chimpanzee
Pan troglodytes
XP_001138236
432
48499
T154
D
P
Q
R
H
P
N
T
L
S
F
R
C
S
L
Rhesus Macaque
Macaca mulatta
XP_001110532
302
34516
I40
N
F
R
I
E
K
K
I
G
R
G
Q
F
S
E
Dog
Lupus familis
XP_851372
313
35673
T35
D
P
Q
R
H
P
N
T
L
S
F
R
C
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES70
313
35724
T35
D
P
Q
R
L
P
N
T
L
S
F
R
C
S
L
Rat
Rattus norvegicus
P59895
313
35817
T35
D
P
Q
R
H
P
N
T
L
S
F
R
C
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509791
504
55648
A225
C
G
S
R
H
L
T
A
Y
P
Y
R
C
A
L
Chicken
Gallus gallus
NP_001012549
314
36302
S36
D
P
Q
R
H
L
T
S
Y
P
Y
R
C
T
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_510080
302
34559
K31
I
I
E
K
K
I
G
K
G
Q
F
S
E
V
F
Sea Urchin
Strong. purpuratus
XP_781870
294
33867
E38
I
G
K
G
Q
F
S
E
V
Y
R
A
R
C
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.7
76.6
96.8
N.A.
95.2
96.1
N.A.
53.7
88.5
N.A.
N.A.
N.A.
N.A.
N.A.
65.1
70.9
Protein Similarity:
100
71.9
85.6
97.4
N.A.
96.4
97.4
N.A.
56.9
91.4
N.A.
N.A.
N.A.
N.A.
N.A.
77.9
83
P-Site Identity:
100
100
6.6
100
N.A.
93.3
100
N.A.
33.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
100
26.6
100
N.A.
93.3
100
N.A.
46.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
10
0
10
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
70
10
0
% C
% Asp:
60
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
10
0
0
10
0
0
0
0
10
0
10
% E
% Phe:
0
10
0
0
0
10
0
0
0
0
60
0
10
0
10
% F
% Gly:
0
20
0
10
0
0
10
0
20
0
10
0
0
0
0
% G
% His:
0
0
0
0
60
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
20
10
0
10
0
10
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
10
10
10
10
10
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
10
20
0
0
50
0
0
0
0
0
80
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
50
0
0
0
0
0
0
0
0
% N
% Pro:
0
60
0
0
0
50
0
0
0
20
0
0
0
0
0
% P
% Gln:
0
0
60
0
10
0
0
0
0
10
0
10
0
0
0
% Q
% Arg:
0
0
10
70
0
0
0
0
0
10
10
70
10
0
0
% R
% Ser:
0
0
10
0
0
0
10
10
0
50
0
10
0
60
0
% S
% Thr:
0
0
0
0
0
0
20
50
0
0
0
0
0
10
0
% T
% Val:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
20
10
20
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _