Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: OTOF All Species: 20.91
Human Site: T597 Identified Species: 51.11
UniProt: Q9HC10 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HC10 NP_004793.2 1997 226753 T597 E V Q V E Q A T P I S E S C A
Chimpanzee Pan troglodytes XP_519944 1857 209286 T563 H P E K P L V T E G N R N Y N
Rhesus Macaque Macaca mulatta XP_001100421 2000 224900 L617 E V E V E E L L P L P E N V L
Dog Lupus familis XP_849758 1997 226776 T597 E V Q V E Q A T P V S E S C T
Cat Felis silvestris
Mouse Mus musculus Q9ESF1 1997 227015 T596 E V Q V E Q A T P V S E S C T
Rat Rattus norvegicus Q9ERC5 1993 226321 T612 E V Q V E Q A T P V S E S C T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511652 1860 209863 E566 Q V S T T Q P E K P L V T D G
Chicken Gallus gallus XP_420015 2010 228657 T607 E V Q V E Q A T P V A D N C T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5SPC5 1992 226210 S602 E V H M E P V S N I S E S A T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393799 1896 219389 E614 E L A V P I I E K S L W R T E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.8 41.5 95.7 N.A. 94.9 93.8 N.A. 46 81.3 N.A. 76.7 N.A. N.A. 33.7 N.A. N.A.
Protein Similarity: 100 66 61.1 98.2 N.A. 97.6 97 N.A. 64.6 91.3 N.A. 88.6 N.A. N.A. 53.8 N.A. N.A.
P-Site Identity: 100 6.6 40 86.6 N.A. 86.6 86.6 N.A. 13.3 66.6 N.A. 46.6 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 100 26.6 66.6 93.3 N.A. 93.3 93.3 N.A. 26.6 93.3 N.A. 60 N.A. N.A. 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 50 0 0 0 10 0 0 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 50 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 0 % D
% Glu: 80 0 20 0 70 10 0 20 10 0 0 60 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 10 % G
% His: 10 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 10 0 0 20 0 0 0 0 0 % I
% Lys: 0 0 0 10 0 0 0 0 20 0 0 0 0 0 0 % K
% Leu: 0 10 0 0 0 10 10 10 0 10 20 0 0 0 10 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 10 0 10 0 30 0 10 % N
% Pro: 0 10 0 0 20 10 10 0 60 10 10 0 0 0 0 % P
% Gln: 10 0 50 0 0 60 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 0 % R
% Ser: 0 0 10 0 0 0 0 10 0 10 50 0 50 0 0 % S
% Thr: 0 0 0 10 10 0 0 60 0 0 0 0 10 10 50 % T
% Val: 0 80 0 70 0 0 20 0 0 40 0 10 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _