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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OTOF
All Species:
22.42
Human Site:
S287
Identified Species:
54.81
UniProt:
Q9HC10
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HC10
NP_004793.2
1997
226753
S287
G
D
D
K
K
Y
T
S
M
K
E
S
T
N
C
Chimpanzee
Pan troglodytes
XP_519944
1857
209286
N265
M
N
S
S
I
M
A
N
V
T
K
A
F
V
G
Rhesus Macaque
Macaca mulatta
XP_001100421
2000
224900
A262
G
G
Q
R
R
V
T
A
T
Q
R
G
T
N
C
Dog
Lupus familis
XP_849758
1997
226776
S287
G
D
D
K
K
C
T
S
M
K
E
S
T
N
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9ESF1
1997
227015
S286
G
D
D
K
K
Y
T
S
M
K
E
S
T
N
C
Rat
Rattus norvegicus
Q9ERC5
1993
226321
S302
G
D
D
K
K
Y
T
S
M
K
E
S
T
N
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511652
1860
209863
P267
I
Y
R
A
E
E
L
P
K
M
N
S
S
I
M
Chicken
Gallus gallus
XP_420015
2010
228657
S297
G
E
E
K
K
Y
T
S
M
K
E
S
T
N
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5SPC5
1992
226210
S292
G
E
E
K
K
Y
T
S
M
K
E
S
T
N
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393799
1896
219389
K314
R
V
G
K
R
K
R
K
T
V
I
R
K
K
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.8
41.5
95.7
N.A.
94.9
93.8
N.A.
46
81.3
N.A.
76.7
N.A.
N.A.
33.7
N.A.
N.A.
Protein Similarity:
100
66
61.1
98.2
N.A.
97.6
97
N.A.
64.6
91.3
N.A.
88.6
N.A.
N.A.
53.8
N.A.
N.A.
P-Site Identity:
100
0
33.3
93.3
N.A.
100
100
N.A.
6.6
86.6
N.A.
86.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
33.3
60
93.3
N.A.
100
100
N.A.
20
100
N.A.
100
N.A.
N.A.
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
10
10
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
70
% C
% Asp:
0
40
40
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
20
20
0
10
10
0
0
0
0
60
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
70
10
10
0
0
0
0
0
0
0
0
10
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
10
0
0
0
0
0
10
0
0
10
0
% I
% Lys:
0
0
0
70
60
10
0
10
10
60
10
0
10
10
0
% K
% Leu:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% L
% Met:
10
0
0
0
0
10
0
0
60
10
0
0
0
0
10
% M
% Asn:
0
10
0
0
0
0
0
10
0
0
10
0
0
70
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
10
0
10
10
20
0
10
0
0
0
10
10
0
0
0
% R
% Ser:
0
0
10
10
0
0
0
60
0
0
0
70
10
0
0
% S
% Thr:
0
0
0
0
0
0
70
0
20
10
0
0
70
0
10
% T
% Val:
0
10
0
0
0
10
0
0
10
10
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
50
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _