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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM165
All Species:
14.55
Human Site:
T87
Identified Species:
32
UniProt:
Q9HC07
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HC07
NP_060945.2
324
34906
T87
T
N
K
E
D
P
A
T
Q
T
N
L
G
F
I
Chimpanzee
Pan troglodytes
XP_001144639
268
29247
E45
D
L
S
H
R
N
K
E
P
P
A
P
A
Q
Q
Rhesus Macaque
Macaca mulatta
XP_001088728
326
35122
T89
T
N
K
E
D
P
A
T
Q
T
N
L
G
F
I
Dog
Lupus familis
XP_532375
325
34592
T88
S
N
K
E
D
P
A
T
Q
T
N
L
G
F
I
Cat
Felis silvestris
Mouse
Mus musculus
P52875
323
34772
A87
T
N
K
E
D
A
A
A
Q
T
N
L
G
F
I
Rat
Rattus norvegicus
Q4V899
323
34791
T87
T
N
R
E
D
A
A
T
Q
A
N
L
G
F
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_997848
305
32923
N67
A
I
R
V
D
E
P
N
K
G
N
L
G
F
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623837
274
30056
L51
L
H
A
F
V
A
S
L
S
V
I
V
V
S
E
Nematode Worm
Caenorhab. elegans
NP_497567
297
32118
S59
Q
K
E
H
K
K
I
S
S
E
D
I
S
F
Y
Sea Urchin
Strong. purpuratus
XP_798718
317
34740
G81
L
D
S
P
G
E
K
G
R
M
D
M
T
F
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38301
280
30322
D56
I
G
L
S
E
I
G
D
K
T
F
L
I
A
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82
97.8
92.6
N.A.
91.6
91.9
N.A.
N.A.
N.A.
N.A.
69.7
N.A.
N.A.
54
47.8
51.8
Protein Similarity:
100
82.4
98.1
94.4
N.A.
93.8
94.7
N.A.
N.A.
N.A.
N.A.
77.4
N.A.
N.A.
65.4
63.8
64.8
P-Site Identity:
100
0
100
93.3
N.A.
86.6
80
N.A.
N.A.
N.A.
N.A.
40
N.A.
N.A.
0
6.6
6.6
P-Site Similarity:
100
0
100
100
N.A.
86.6
86.6
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
20
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
28
46
10
0
10
10
0
10
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
0
55
0
0
10
0
0
19
0
0
0
0
% D
% Glu:
0
0
10
46
10
19
0
10
0
10
0
0
0
0
10
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
10
0
0
73
0
% F
% Gly:
0
10
0
0
10
0
10
10
0
10
0
0
55
0
0
% G
% His:
0
10
0
19
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
0
0
10
10
0
0
0
10
10
10
0
55
% I
% Lys:
0
10
37
0
10
10
19
0
19
0
0
0
0
0
0
% K
% Leu:
19
10
10
0
0
0
0
10
0
0
0
64
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% M
% Asn:
0
46
0
0
0
10
0
10
0
0
55
0
0
0
0
% N
% Pro:
0
0
0
10
0
28
10
0
10
10
0
10
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
46
0
0
0
0
10
10
% Q
% Arg:
0
0
19
0
10
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
10
0
19
10
0
0
10
10
19
0
0
0
10
10
0
% S
% Thr:
37
0
0
0
0
0
0
37
0
46
0
0
10
0
0
% T
% Val:
0
0
0
10
10
0
0
0
0
10
0
10
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _