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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM165
All Species:
15.45
Human Site:
T218
Identified Species:
34
UniProt:
Q9HC07
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HC07
NP_060945.2
324
34906
T218
N
G
P
G
D
V
E
T
G
T
S
I
T
V
P
Chimpanzee
Pan troglodytes
XP_001144639
268
29247
S163
R
V
Y
T
Y
Y
V
S
T
V
L
F
A
I
F
Rhesus Macaque
Macaca mulatta
XP_001088728
326
35122
T220
N
G
P
G
D
V
E
T
G
T
S
I
T
V
P
Dog
Lupus familis
XP_532375
325
34592
T219
N
G
P
G
D
V
E
T
G
A
S
T
A
I
P
Cat
Felis silvestris
Mouse
Mus musculus
P52875
323
34772
T217
L
N
G
P
D
V
E
T
G
T
S
T
A
I
P
Rat
Rattus norvegicus
Q4V899
323
34791
T217
L
N
G
P
D
V
E
T
G
T
S
T
A
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_997848
305
32923
G199
G
A
P
D
V
E
A
G
T
A
A
N
M
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623837
274
30056
G169
L
V
Q
D
P
E
T
G
V
I
R
K
A
T
K
Nematode Worm
Caenorhab. elegans
NP_497567
297
32118
G188
F
E
M
L
E
G
G
G
G
V
A
S
Q
S
E
Sea Urchin
Strong. purpuratus
XP_798718
317
34740
S212
T
L
T
Q
D
P
E
S
G
I
I
R
G
G
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38301
280
30322
G174
Q
L
K
N
A
S
I
G
K
K
I
V
H
R
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82
97.8
92.6
N.A.
91.6
91.9
N.A.
N.A.
N.A.
N.A.
69.7
N.A.
N.A.
54
47.8
51.8
Protein Similarity:
100
82.4
98.1
94.4
N.A.
93.8
94.7
N.A.
N.A.
N.A.
N.A.
77.4
N.A.
N.A.
65.4
63.8
64.8
P-Site Identity:
100
0
100
73.3
N.A.
53.3
53.3
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
0
6.6
20
P-Site Similarity:
100
13.3
100
80
N.A.
60
60
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
0
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
0
10
0
0
19
19
0
46
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
19
55
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
0
10
19
55
0
0
0
0
0
0
0
10
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% F
% Gly:
10
28
19
28
0
10
10
37
64
0
0
0
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
19
19
19
0
37
10
% I
% Lys:
0
0
10
0
0
0
0
0
10
10
0
10
0
0
10
% K
% Leu:
28
19
0
10
0
0
0
0
0
0
10
0
0
10
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
28
19
0
10
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
37
19
10
10
0
0
0
0
0
0
0
0
55
% P
% Gln:
10
0
10
10
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
10
10
0
10
0
% R
% Ser:
0
0
0
0
0
10
0
19
0
0
46
10
0
10
0
% S
% Thr:
10
0
10
10
0
0
10
46
19
37
0
28
19
10
0
% T
% Val:
0
19
0
0
10
46
10
0
10
19
0
10
0
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
10
10
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _