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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM165
All Species:
30
Human Site:
S182
Identified Species:
66
UniProt:
Q9HC07
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HC07
NP_060945.2
324
34906
S182
L
R
E
G
L
K
M
S
P
D
E
G
Q
E
E
Chimpanzee
Pan troglodytes
XP_001144639
268
29247
L137
L
A
G
A
M
L
A
L
G
L
M
T
C
L
S
Rhesus Macaque
Macaca mulatta
XP_001088728
326
35122
S184
L
R
E
G
L
K
M
S
P
D
E
G
Q
E
E
Dog
Lupus familis
XP_532375
325
34592
S183
L
R
E
G
L
K
M
S
P
D
E
G
Q
E
E
Cat
Felis silvestris
Mouse
Mus musculus
P52875
323
34772
S182
L
R
E
G
L
K
M
S
P
D
E
G
Q
E
E
Rat
Rattus norvegicus
Q4V899
323
34791
S182
L
R
E
G
L
K
M
S
P
D
E
G
Q
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_997848
305
32923
S162
L
R
E
G
L
R
M
S
P
D
E
G
Q
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623837
274
30056
V143
G
Q
E
E
L
E
E
V
Q
S
D
L
R
K
R
Nematode Worm
Caenorhab. elegans
NP_497567
297
32118
S154
L
H
E
G
W
T
M
S
P
N
E
G
Q
E
G
Sea Urchin
Strong. purpuratus
XP_798718
317
34740
S176
L
R
E
G
W
S
M
S
P
D
E
G
Q
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38301
280
30322
D148
E
E
E
I
A
I
K
D
M
N
Q
D
M
D
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82
97.8
92.6
N.A.
91.6
91.9
N.A.
N.A.
N.A.
N.A.
69.7
N.A.
N.A.
54
47.8
51.8
Protein Similarity:
100
82.4
98.1
94.4
N.A.
93.8
94.7
N.A.
N.A.
N.A.
N.A.
77.4
N.A.
N.A.
65.4
63.8
64.8
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
N.A.
13.3
66.6
86.6
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
N.A.
46.6
73.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
10
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
64
10
10
0
10
10
% D
% Glu:
10
10
91
10
0
10
10
0
0
0
73
0
0
73
64
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
73
0
0
0
0
10
0
0
73
0
0
10
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
46
10
0
0
0
0
0
0
10
0
% K
% Leu:
82
0
0
0
64
10
0
10
0
10
0
10
0
10
0
% L
% Met:
0
0
0
0
10
0
73
0
10
0
10
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
19
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
73
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
10
0
10
0
73
0
0
% Q
% Arg:
0
64
0
0
0
10
0
0
0
0
0
0
10
0
10
% R
% Ser:
0
0
0
0
0
10
0
73
0
10
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% T
% Val:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _