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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PARVB All Species: 44.55
Human Site: Y354 Identified Species: 75.38
UniProt: Q9HBI1 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HBI1 NP_001003828.1 364 41714 Y354 K S T L R V L Y N L F T K Y K
Chimpanzee Pan troglodytes XP_001171467 372 42228 Y362 K S T L R V L Y N L F T K Y R
Rhesus Macaque Macaca mulatta XP_001106273 282 31975 R273 C S V L L S H R G Q D L A N V
Dog Lupus familis XP_538336 393 44396 Y383 K S T L R V L Y N L F T K Y K
Cat Felis silvestris
Mouse Mus musculus Q9ES46 365 41651 Y355 K S T L R V L Y T L F T K Y K
Rat Rattus norvegicus Q9HB97 372 42273 Y362 K S T L R V L Y N L F T K Y R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519401 299 34345 N290 S T L R V L N N L Y V R Y K N
Chicken Gallus gallus XP_416459 365 41865 Y355 K S T L R V L Y N L F T K Y K
Frog Xenopus laevis NP_001089519 365 41596 Y355 K S T L R V L Y N L F T K Y K
Zebra Danio Brachydanio rerio NP_956020 365 41402 Y355 K S T L R V L Y N L F T N Y K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608352 367 41845 Y357 K S T L R V L Y S L F T M F R
Honey Bee Apis mellifera XP_393249 365 41734 Y355 K S T L R V L Y N L F T K Y K
Nematode Worm Caenorhab. elegans O16785 375 42983 H366 K S T L R L L H L L F T K Y K
Sea Urchin Strong. purpuratus XP_785434 360 41100 Y350 K S T L R V L Y N I F T K Y K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.1 70.3 81.4 N.A. 92 73.6 N.A. 62.6 90.9 85.4 74.5 N.A. 58.8 63.2 47.2 61.2
Protein Similarity: 100 85.4 71.6 86.5 N.A. 96.9 85.4 N.A. 72.5 96.7 93.9 87.9 N.A. 74.3 79.4 67.4 79.4
P-Site Identity: 100 93.3 13.3 100 N.A. 93.3 93.3 N.A. 0 100 100 93.3 N.A. 73.3 100 80 93.3
P-Site Similarity: 100 100 13.3 100 N.A. 93.3 100 N.A. 13.3 100 100 93.3 N.A. 93.3 100 93.3 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 86 0 0 8 0 % F
% Gly: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % I
% Lys: 86 0 0 0 0 0 0 0 0 0 0 0 72 8 65 % K
% Leu: 0 0 8 93 8 15 86 0 15 79 0 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 0 0 0 8 8 65 0 0 0 8 8 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % Q
% Arg: 0 0 0 8 86 0 0 8 0 0 0 8 0 0 22 % R
% Ser: 8 93 0 0 0 8 0 0 8 0 0 0 0 0 0 % S
% Thr: 0 8 86 0 0 0 0 0 8 0 0 86 0 0 0 % T
% Val: 0 0 8 0 8 79 0 0 0 0 8 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 79 0 8 0 0 8 79 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _