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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKNK2
All Species:
23.94
Human Site:
S51
Identified Species:
47.88
UniProt:
Q9HBH9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HBH9
NP_060042.2
465
51875
S51
A
R
P
D
M
P
A
S
Q
P
I
D
I
P
D
Chimpanzee
Pan troglodytes
XP_512248
805
84821
S48
A
S
G
I
P
L
S
S
D
C
R
Q
R
M
D
Rhesus Macaque
Macaca mulatta
XP_001117579
489
54064
S75
A
R
P
D
M
P
A
S
Q
P
I
D
I
P
D
Dog
Lupus familis
XP_855041
1044
109683
M640
E
C
P
A
R
P
D
M
P
A
S
Q
P
I
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDB0
459
51614
S51
A
R
P
D
M
P
S
S
Q
P
I
D
I
P
D
Rat
Rattus norvegicus
Q5U2N4
459
51555
S51
A
R
P
D
M
P
S
S
Q
P
I
D
I
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235171
508
56331
S100
S
P
K
E
M
V
S
S
Q
P
L
A
I
A
D
Frog
Xenopus laevis
Q6P431
467
52653
A51
R
P
D
V
P
S
S
A
P
I
D
I
P
D
A
Zebra Danio
Brachydanio rerio
NP_997888
472
52923
S51
T
R
P
A
M
P
S
S
Q
P
I
D
I
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_731624
1090
123424
K45
R
H
K
E
E
M
Q
K
K
R
R
K
K
R
I
Honey Bee
Apis mellifera
XP_395927
516
58135
S45
K
K
K
R
S
G
S
S
L
M
S
S
C
F
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_779905
511
56921
S77
E
Q
M
D
L
M
M
S
I
S
S
V
E
D
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.8
92.4
34.6
N.A.
92.6
92.6
N.A.
N.A.
60.8
76.8
73.3
N.A.
24
49.8
N.A.
48.7
Protein Similarity:
100
48.5
93.4
36.8
N.A.
95.2
95.2
N.A.
N.A.
73
87.7
84.5
N.A.
31
66.6
N.A.
64.5
P-Site Identity:
100
20
100
20
N.A.
93.3
93.3
N.A.
N.A.
40
0
80
N.A.
0
6.6
N.A.
13.3
P-Site Similarity:
100
26.6
100
20
N.A.
100
100
N.A.
N.A.
66.6
13.3
86.6
N.A.
13.3
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
42
0
0
17
0
0
17
9
0
9
0
9
0
9
9
% A
% Cys:
0
9
0
0
0
0
0
0
0
9
0
0
9
0
0
% C
% Asp:
0
0
9
42
0
0
9
0
9
0
9
42
0
17
67
% D
% Glu:
17
0
0
17
9
0
0
0
0
0
0
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% F
% Gly:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
0
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
0
9
9
42
9
50
9
9
% I
% Lys:
9
9
25
0
0
0
0
9
9
0
0
9
9
0
0
% K
% Leu:
0
0
0
0
9
9
0
0
9
0
9
0
0
0
0
% L
% Met:
0
0
9
0
50
17
9
9
0
9
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
17
50
0
17
50
0
0
17
50
0
0
17
42
0
% P
% Gln:
0
9
0
0
0
0
9
0
50
0
0
17
0
0
9
% Q
% Arg:
17
42
0
9
9
0
0
0
0
9
17
0
9
9
0
% R
% Ser:
9
9
0
0
9
9
59
75
0
9
25
9
0
0
0
% S
% Thr:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
9
0
9
0
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _