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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKNK2
All Species:
27.88
Human Site:
S169
Identified Species:
55.76
UniProt:
Q9HBH9
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HBH9
NP_060042.2
465
51875
S169
M
R
G
G
S
I
L
S
H
I
H
K
R
R
H
Chimpanzee
Pan troglodytes
XP_512248
805
84821
S450
K
R
G
R
A
T
D
S
F
S
G
R
F
E
D
Rhesus Macaque
Macaca mulatta
XP_001117579
489
54064
S193
M
R
G
G
S
I
L
S
H
I
H
K
R
R
H
Dog
Lupus familis
XP_855041
1044
109683
S761
M
R
G
G
S
I
L
S
H
I
H
K
R
R
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDB0
459
51614
S169
M
R
G
G
S
I
L
S
H
I
H
R
R
R
H
Rat
Rattus norvegicus
Q5U2N4
459
51555
S169
M
R
G
G
S
I
L
S
H
I
H
R
R
R
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235171
508
56331
A217
L
R
G
G
S
I
L
A
H
I
Q
K
R
K
H
Frog
Xenopus laevis
Q6P431
467
52653
N168
M
C
G
G
S
I
L
N
H
I
H
R
R
R
H
Zebra Danio
Brachydanio rerio
NP_997888
472
52923
T169
L
R
G
G
S
I
L
T
H
I
H
R
R
Q
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_731624
1090
123424
S151
I
N
G
G
P
L
L
S
R
I
Q
E
H
I
C
Honey Bee
Apis mellifera
XP_395927
516
58135
S150
I
Q
E
R
I
H
F
S
E
R
E
A
S
Q
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_779905
511
56921
Q200
M
Y
G
G
A
L
L
Q
H
I
E
Q
R
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.8
92.4
34.6
N.A.
92.6
92.6
N.A.
N.A.
60.8
76.8
73.3
N.A.
24
49.8
N.A.
48.7
Protein Similarity:
100
48.5
93.4
36.8
N.A.
95.2
95.2
N.A.
N.A.
73
87.7
84.5
N.A.
31
66.6
N.A.
64.5
P-Site Identity:
100
20
100
100
N.A.
93.3
93.3
N.A.
N.A.
73.3
80
73.3
N.A.
33.3
6.6
N.A.
46.6
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
100
N.A.
53.3
26.6
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
17
0
0
9
0
0
0
9
0
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% D
% Glu:
0
0
9
0
0
0
0
0
9
0
17
9
0
9
0
% E
% Phe:
0
0
0
0
0
0
9
0
9
0
0
0
9
0
0
% F
% Gly:
0
0
92
84
0
0
0
0
0
0
9
0
0
9
0
% G
% His:
0
0
0
0
0
9
0
0
75
0
59
0
9
0
67
% H
% Ile:
17
0
0
0
9
67
0
0
0
84
0
0
0
9
9
% I
% Lys:
9
0
0
0
0
0
0
0
0
0
0
34
0
9
0
% K
% Leu:
17
0
0
0
0
17
84
0
0
0
0
0
0
0
0
% L
% Met:
59
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
0
9
0
0
17
9
0
17
0
% Q
% Arg:
0
67
0
17
0
0
0
0
9
9
0
42
75
50
0
% R
% Ser:
0
0
0
0
67
0
0
67
0
9
0
0
9
0
0
% S
% Thr:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
9
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _