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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C12orf10
All Species:
18.48
Human Site:
T159
Identified Species:
33.89
UniProt:
Q9HB07
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HB07
NP_067653
376
42445
T159
E
E
D
S
M
V
G
T
L
Y
D
K
M
Y
E
Chimpanzee
Pan troglodytes
XP_522402
376
42518
T159
E
E
D
S
M
V
G
T
L
Y
D
K
M
Y
E
Rhesus Macaque
Macaca mulatta
XP_001104094
376
42450
T159
E
E
D
S
M
V
G
T
L
Y
D
K
M
Y
E
Dog
Lupus familis
XP_849816
358
40144
N153
E
E
V
D
A
V
D
N
G
I
S
Q
W
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JK81
380
42704
T158
E
E
D
S
V
V
D
T
I
Y
D
K
M
Y
E
Rat
Rattus norvegicus
Q641W2
381
42870
T159
E
E
D
S
V
V
D
T
I
Y
D
K
M
Y
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423851
370
41355
A154
E
D
S
P
A
V
T
A
L
Y
D
K
L
Y
E
Frog
Xenopus laevis
NP_001088807
369
41920
V161
E
E
D
P
I
I
S
V
L
Y
D
K
M
Y
E
Zebra Danio
Brachydanio rerio
NP_001035070
273
31376
Q80
S
F
H
S
V
C
A
Q
K
P
W
V
T
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623698
329
37728
I136
F
I
Q
E
I
D
S
I
D
N
G
I
S
I
C
Nematode Worm
Caenorhab. elegans
O17606
340
38446
S147
D
G
V
P
R
Y
H
S
S
G
N
L
S
S
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_199012
373
42281
V165
V
L
R
L
F
L
A
V
Y
K
S
F
M
E
A
Baker's Yeast
Sacchar. cerevisiae
P40093
338
38156
K145
A
N
D
N
G
I
S
K
Y
T
I
P
K
D
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96
84
N.A.
85.5
85.8
N.A.
N.A.
56.1
64
43.8
N.A.
N.A.
43.6
41.7
N.A.
Protein Similarity:
100
99.1
97.6
88.3
N.A.
90.7
90.2
N.A.
N.A.
69.4
75
55.5
N.A.
N.A.
61.4
61.4
N.A.
P-Site Identity:
100
100
100
26.6
N.A.
80
80
N.A.
N.A.
53.3
66.6
6.6
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
100
100
100
33.3
N.A.
93.3
93.3
N.A.
N.A.
66.6
80
13.3
N.A.
N.A.
6.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
46
40.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63
59.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
16
0
16
8
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
8
54
8
0
8
24
0
8
0
54
0
0
8
0
% D
% Glu:
62
54
0
8
0
0
0
0
0
0
0
0
0
16
62
% E
% Phe:
8
8
0
0
8
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
8
0
0
8
0
24
0
8
8
8
0
0
0
0
% G
% His:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
16
16
0
8
16
8
8
8
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
8
8
8
0
54
8
8
0
% K
% Leu:
0
8
0
8
0
8
0
0
39
0
0
8
8
0
8
% L
% Met:
0
0
0
0
24
0
0
0
0
0
0
0
54
0
0
% M
% Asn:
0
8
0
8
0
0
0
8
0
8
8
0
0
0
0
% N
% Pro:
0
0
0
24
0
0
0
0
0
8
0
8
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
8
0
0
0
8
0
0
0
% Q
% Arg:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
8
0
8
47
0
0
24
8
8
0
16
0
16
8
8
% S
% Thr:
0
0
0
0
0
0
8
39
0
8
0
0
8
0
0
% T
% Val:
8
0
16
0
24
54
0
16
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
16
54
0
0
0
54
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _