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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C12orf10
All Species:
27.27
Human Site:
S315
Identified Species:
50
UniProt:
Q9HB07
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HB07
NP_067653
376
42445
S315
K
E
P
H
S
F
Q
S
R
L
P
L
P
E
P
Chimpanzee
Pan troglodytes
XP_522402
376
42518
S315
K
E
P
H
S
F
Q
S
R
L
P
L
P
E
P
Rhesus Macaque
Macaca mulatta
XP_001104094
376
42450
S315
K
E
P
H
S
F
Q
S
R
L
P
L
P
E
P
Dog
Lupus familis
XP_849816
358
40144
S291
K
E
P
H
S
F
Q
S
R
L
P
L
P
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9JK81
380
42704
S314
K
E
P
H
S
F
Q
S
R
L
P
L
P
E
P
Rat
Rattus norvegicus
Q641W2
381
42870
S315
K
E
P
H
S
F
Q
S
R
L
P
L
P
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423851
370
41355
S309
V
G
P
R
S
F
E
S
R
L
P
L
P
E
P
Frog
Xenopus laevis
NP_001088807
369
41920
F314
V
P
T
G
P
N
T
F
Q
N
R
L
S
L
P
Zebra Danio
Brachydanio rerio
NP_001035070
273
31376
Q218
H
Q
V
D
V
S
G
Q
V
L
L
L
Q
Q
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623698
329
37728
L274
P
D
S
F
I
C
R
L
F
L
P
E
S
W
E
Nematode Worm
Caenorhab. elegans
O17606
340
38446
L285
L
P
A
A
W
R
G
L
R
D
D
D
L
S
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_199012
373
42281
R317
A
V
A
V
A
P
D
R
F
E
N
R
K
P
L
Baker's Yeast
Sacchar. cerevisiae
P40093
338
38156
S283
T
V
P
I
N
S
T
S
F
Q
F
R
R
G
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96
84
N.A.
85.5
85.8
N.A.
N.A.
56.1
64
43.8
N.A.
N.A.
43.6
41.7
N.A.
Protein Similarity:
100
99.1
97.6
88.3
N.A.
90.7
90.2
N.A.
N.A.
69.4
75
55.5
N.A.
N.A.
61.4
61.4
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
73.3
13.3
13.3
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
80
20
26.6
N.A.
N.A.
26.6
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
46
40.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63
59.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
16
8
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
0
0
8
0
0
8
8
8
0
0
0
% D
% Glu:
0
47
0
0
0
0
8
0
0
8
0
8
0
54
8
% E
% Phe:
0
0
0
8
0
54
0
8
24
0
8
0
0
0
0
% F
% Gly:
0
8
0
8
0
0
16
0
0
0
0
0
0
8
8
% G
% His:
8
0
0
47
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
47
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% K
% Leu:
8
0
0
0
0
0
0
16
0
70
8
70
8
8
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
8
0
0
0
8
8
0
0
0
0
% N
% Pro:
8
16
62
0
8
8
0
0
0
0
62
0
54
8
62
% P
% Gln:
0
8
0
0
0
0
47
8
8
8
0
0
8
8
0
% Q
% Arg:
0
0
0
8
0
8
8
8
62
0
8
16
8
0
0
% R
% Ser:
0
0
8
0
54
16
0
62
0
0
0
0
16
8
0
% S
% Thr:
8
0
8
0
0
0
16
0
0
0
0
0
0
0
0
% T
% Val:
16
16
8
8
8
0
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _