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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C12orf10 All Species: 26.06
Human Site: S130 Identified Species: 47.78
UniProt: Q9HB07 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HB07 NP_067653 376 42445 S130 K P W Q T K L S S A G L I Y L
Chimpanzee Pan troglodytes XP_522402 376 42518 S130 K P W Q T K L S S A G L I Y L
Rhesus Macaque Macaca mulatta XP_001104094 376 42450 S130 K P W Q T K L S S A G L I Y L
Dog Lupus familis XP_849816 358 40144 L124 H K L L A Q L L G T S E E D S
Cat Felis silvestris
Mouse Mus musculus Q9JK81 380 42704 S129 K P W Q T K L S S A G L V Y L
Rat Rattus norvegicus Q641W2 381 42870 S130 K P W Q T K L S S A G L V Y L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423851 370 41355 S125 K P W T T K L S S A G L V Y C
Frog Xenopus laevis NP_001088807 369 41920 S132 K P W V T K L S S A G L V Y A
Zebra Danio Brachydanio rerio NP_001035070 273 31376 D51 A E C D V V V D V G G E Y D H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623698 329 37728 K107 H F G H E I I K E L V P Q A S
Nematode Worm Caenorhab. elegans O17606 340 38446 Y118 S S M I D L F Y H R L Y E Q F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199012 373 42281 V136 K L S S A G L V Y K H F G K E
Baker's Yeast Sacchar. cerevisiae P40093 338 38156 V116 K T I L N N K V S S S D L D L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 96 84 N.A. 85.5 85.8 N.A. N.A. 56.1 64 43.8 N.A. N.A. 43.6 41.7 N.A.
Protein Similarity: 100 99.1 97.6 88.3 N.A. 90.7 90.2 N.A. N.A. 69.4 75 55.5 N.A. N.A. 61.4 61.4 N.A.
P-Site Identity: 100 100 100 6.6 N.A. 93.3 93.3 N.A. N.A. 80 80 6.6 N.A. N.A. 0 0 N.A.
P-Site Similarity: 100 100 100 13.3 N.A. 100 100 N.A. N.A. 86.6 86.6 13.3 N.A. N.A. 6.6 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 46 40.6 N.A.
Protein Similarity: N.A. N.A. N.A. 63 59.3 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 16 0 0 0 0 54 0 0 0 8 8 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 0 8 8 0 0 8 0 0 0 8 0 24 0 % D
% Glu: 0 8 0 0 8 0 0 0 8 0 0 16 16 0 8 % E
% Phe: 0 8 0 0 0 0 8 0 0 0 0 8 0 0 8 % F
% Gly: 0 0 8 0 0 8 0 0 8 8 62 0 8 0 0 % G
% His: 16 0 0 8 0 0 0 0 8 0 8 0 0 0 8 % H
% Ile: 0 0 8 8 0 8 8 0 0 0 0 0 24 0 0 % I
% Lys: 70 8 0 0 0 54 8 8 0 8 0 0 0 8 0 % K
% Leu: 0 8 8 16 0 8 70 8 0 8 8 54 8 0 47 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 54 0 0 0 0 0 0 0 0 0 8 0 0 0 % P
% Gln: 0 0 0 39 0 8 0 0 0 0 0 0 8 8 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % R
% Ser: 8 8 8 8 0 0 0 54 62 8 16 0 0 0 16 % S
% Thr: 0 8 0 8 54 0 0 0 0 8 0 0 0 0 0 % T
% Val: 0 0 0 8 8 8 8 16 8 0 8 0 31 0 0 % V
% Trp: 0 0 54 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 8 0 0 8 8 54 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _