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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLK4
All Species:
36.67
Human Site:
Y409
Identified Species:
67.22
UniProt:
Q9HAZ1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAZ1
NP_065717.1
481
57492
Y409
Q
K
T
R
K
R
K
Y
F
H
H
N
Q
L
D
Chimpanzee
Pan troglodytes
XP_001148409
445
52800
Y373
Q
K
T
R
K
R
K
Y
F
H
H
N
Q
L
D
Rhesus Macaque
Macaca mulatta
XP_001097751
481
57494
Y409
Q
K
T
R
K
R
K
Y
F
H
H
N
Q
L
D
Dog
Lupus familis
XP_531875
481
57271
Y409
Q
K
T
R
K
R
K
Y
F
H
H
N
Q
L
D
Cat
Felis silvestris
Mouse
Mus musculus
O35493
481
57326
Y409
Q
K
T
R
K
R
K
Y
F
H
H
N
Q
L
D
Rat
Rattus norvegicus
Q63117
490
58467
Y406
H
R
T
R
K
Q
K
Y
F
Y
K
G
G
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505282
480
57495
Y408
Q
K
T
R
K
R
K
Y
F
H
H
N
Q
L
D
Chicken
Gallus gallus
Q5ZIU3
526
59419
C390
S
K
G
Y
P
R
Y
C
T
I
T
T
L
S
D
Frog
Xenopus laevis
NP_001091432
462
54946
Y391
Q
K
T
R
K
H
K
Y
F
Y
H
D
R
L
D
Zebra Danio
Brachydanio rerio
NP_001038344
526
62655
Y437
R
K
T
R
K
Q
K
Y
F
Y
R
G
R
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49762
832
95705
Y733
Y
S
K
T
K
T
K
Y
F
Y
H
G
K
L
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
L372
G
A
T
S
R
D
S
L
K
A
V
L
K
L
P
Baker's Yeast
Sacchar. cerevisiae
P32350
737
83824
K577
D
K
M
F
Y
K
S
K
H
K
L
G
N
S
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.8
99.3
98.1
N.A.
97
52
N.A.
90.8
22
68.1
53.4
N.A.
31.8
N.A.
N.A.
N.A.
Protein Similarity:
100
91.4
99.7
99.1
N.A.
98.5
66.7
N.A.
94.1
39.1
78.5
68
N.A.
43.7
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
46.6
N.A.
100
20
73.3
60
N.A.
46.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
66.6
N.A.
100
20
93.3
86.6
N.A.
60
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.7
26.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.2
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
8
0
0
0
0
0
8
0
0
77
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
77
0
0
0
0
0
0
% F
% Gly:
8
0
8
0
0
0
0
0
0
0
0
31
8
0
0
% G
% His:
8
0
0
0
0
8
0
0
8
47
62
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
77
8
0
77
8
77
8
8
8
8
0
16
0
0
% K
% Leu:
0
0
0
0
0
0
0
8
0
0
8
8
8
85
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
47
8
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
16
% P
% Gln:
54
0
0
0
0
16
0
0
0
0
0
0
47
0
0
% Q
% Arg:
8
8
0
70
8
54
0
0
0
0
8
0
16
0
0
% R
% Ser:
8
8
0
8
0
0
16
0
0
0
0
0
0
16
0
% S
% Thr:
0
0
77
8
0
8
0
0
8
0
8
8
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
8
0
8
77
0
31
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _