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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLK4
All Species:
23.64
Human Site:
T461
Identified Species:
43.33
UniProt:
Q9HAZ1
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAZ1
NP_065717.1
481
57492
T461
R
M
L
E
Y
D
P
T
Q
R
I
T
L
D
E
Chimpanzee
Pan troglodytes
XP_001148409
445
52800
T425
R
M
L
E
Y
D
P
T
Q
R
I
T
L
D
E
Rhesus Macaque
Macaca mulatta
XP_001097751
481
57494
T461
R
M
L
E
Y
D
P
T
Q
R
I
T
L
D
E
Dog
Lupus familis
XP_531875
481
57271
V461
R
M
L
E
Y
D
P
V
K
R
I
T
L
D
E
Cat
Felis silvestris
Mouse
Mus musculus
O35493
481
57326
A461
R
M
L
E
Y
D
P
A
R
R
I
T
L
D
E
Rat
Rattus norvegicus
Q63117
490
58467
A458
R
M
L
E
F
D
P
A
Q
R
I
T
L
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505282
480
57495
N460
R
M
L
E
Y
D
P
N
K
R
I
T
L
D
E
Chicken
Gallus gallus
Q5ZIU3
526
59419
A446
Q
C
L
E
W
D
P
A
I
R
M
T
P
S
Q
Frog
Xenopus laevis
NP_001091432
462
54946
A443
R
M
L
E
Y
D
P
A
K
R
I
T
L
E
E
Zebra Danio
Brachydanio rerio
NP_001038344
526
62655
S489
A
M
L
E
Y
E
P
S
K
R
L
T
L
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49762
832
95705
S785
K
M
L
E
Y
E
P
S
S
R
I
T
L
G
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
S409
G
L
L
R
F
D
P
S
E
R
I
T
A
R
E
Baker's Yeast
Sacchar. cerevisiae
P32350
737
83824
T706
K
M
F
E
F
D
P
T
K
R
I
T
A
K
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.8
99.3
98.1
N.A.
97
52
N.A.
90.8
22
68.1
53.4
N.A.
31.8
N.A.
N.A.
N.A.
Protein Similarity:
100
91.4
99.7
99.1
N.A.
98.5
66.7
N.A.
94.1
39.1
78.5
68
N.A.
43.7
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
80
N.A.
86.6
40
80
53.3
N.A.
66.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
86.6
N.A.
93.3
66.6
93.3
80
N.A.
86.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.7
26.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.2
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
31
0
0
0
0
16
16
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
85
0
0
0
0
0
0
0
47
8
% D
% Glu:
0
0
0
93
0
16
0
0
8
0
0
0
0
8
77
% E
% Phe:
0
0
8
0
24
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
85
0
0
0
0
% I
% Lys:
16
0
0
0
0
0
0
0
39
0
0
0
0
8
0
% K
% Leu:
0
8
93
0
0
0
0
0
0
0
8
0
77
0
0
% L
% Met:
0
85
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
100
0
0
0
0
0
8
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
31
0
0
0
0
0
8
% Q
% Arg:
62
0
0
8
0
0
0
0
8
100
0
0
0
8
0
% R
% Ser:
0
0
0
0
0
0
0
24
8
0
0
0
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
31
0
0
0
100
0
0
0
% T
% Val:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
70
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _