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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLK4
All Species:
18.18
Human Site:
S26
Identified Species:
33.33
UniProt:
Q9HAZ1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAZ1
NP_065717.1
481
57492
S26
G
H
E
S
Y
R
G
S
H
K
R
K
R
R
S
Chimpanzee
Pan troglodytes
XP_001148409
445
52800
L26
H
Y
L
E
A
R
S
L
N
E
R
D
Y
R
D
Rhesus Macaque
Macaca mulatta
XP_001097751
481
57494
S26
G
H
E
S
Y
R
G
S
H
K
R
K
R
R
S
Dog
Lupus familis
XP_531875
481
57271
S26
G
H
E
S
Y
S
G
S
H
K
R
K
R
R
S
Cat
Felis silvestris
Mouse
Mus musculus
O35493
481
57326
S26
G
H
E
S
Y
S
G
S
H
K
R
K
R
R
S
Rat
Rattus norvegicus
Q63117
490
58467
E41
L
R
Y
P
S
R
R
E
P
P
P
R
R
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505282
480
57495
S26
E
H
E
S
Y
G
C
S
Y
K
R
K
K
R
F
Chicken
Gallus gallus
Q5ZIU3
526
59419
R26
F
E
D
N
S
N
K
R
T
V
L
T
T
Q
P
Frog
Xenopus laevis
NP_001091432
462
54946
S26
K
C
Y
K
R
K
R
S
Q
S
S
E
E
E
R
Zebra Danio
Brachydanio rerio
NP_001038344
526
62655
R54
S
E
R
E
R
R
A
R
G
H
R
Q
D
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49762
832
95705
N346
P
Y
A
Y
P
K
P
N
Q
M
Q
P
V
K
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
W26
R
K
R
A
R
L
G
W
D
V
L
P
Q
A
T
Baker's Yeast
Sacchar. cerevisiae
P32350
737
83824
T155
N
N
N
N
N
I
V
T
S
N
N
P
G
C
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.8
99.3
98.1
N.A.
97
52
N.A.
90.8
22
68.1
53.4
N.A.
31.8
N.A.
N.A.
N.A.
Protein Similarity:
100
91.4
99.7
99.1
N.A.
98.5
66.7
N.A.
94.1
39.1
78.5
68
N.A.
43.7
N.A.
N.A.
N.A.
P-Site Identity:
100
20
100
93.3
N.A.
93.3
13.3
N.A.
60
0
6.6
13.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
100
93.3
N.A.
93.3
20
N.A.
73.3
20
20
20
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.7
26.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.2
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
0
8
0
0
0
0
0
0
8
0
% A
% Cys:
0
8
0
0
0
0
8
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
8
0
0
0
0
0
8
0
0
8
8
0
8
% D
% Glu:
8
16
39
16
0
0
0
8
0
8
0
8
8
8
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
31
0
0
0
0
8
39
0
8
0
0
0
8
0
16
% G
% His:
8
39
0
0
0
0
0
0
31
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
8
0
8
0
16
8
0
0
39
0
39
8
8
0
% K
% Leu:
8
0
8
0
0
8
0
8
0
0
16
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
8
8
8
16
8
8
0
8
8
8
8
0
0
0
0
% N
% Pro:
8
0
0
8
8
0
8
0
8
8
8
24
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
16
0
8
8
8
8
0
% Q
% Arg:
8
8
16
0
24
39
16
16
0
0
54
8
39
47
16
% R
% Ser:
8
0
0
39
16
16
8
47
8
8
8
0
0
8
31
% S
% Thr:
0
0
0
0
0
0
0
8
8
0
0
8
8
8
8
% T
% Val:
0
0
0
0
0
0
8
0
0
16
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
16
16
8
39
0
0
0
8
0
0
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _