KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLK4
All Species:
14.85
Human Site:
S126
Identified Species:
27.22
UniProt:
Q9HAZ1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAZ1
NP_065717.1
481
57492
S126
R
H
C
S
S
H
Q
S
R
S
K
S
H
R
R
Chimpanzee
Pan troglodytes
XP_001148409
445
52800
V126
L
R
A
R
Y
E
I
V
D
T
L
G
E
G
A
Rhesus Macaque
Macaca mulatta
XP_001097751
481
57494
S126
R
H
C
S
S
H
Q
S
R
S
K
S
H
R
R
Dog
Lupus familis
XP_531875
481
57271
S126
R
H
C
S
S
H
Q
S
R
S
K
S
H
R
R
Cat
Felis silvestris
Mouse
Mus musculus
O35493
481
57326
S126
R
P
C
A
S
H
Q
S
H
S
K
S
H
R
R
Rat
Rattus norvegicus
Q63117
490
58467
E141
R
S
V
E
D
D
K
E
G
H
L
V
C
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505282
480
57495
H126
H
C
S
S
H
Q
S
H
S
R
S
H
R
R
K
Chicken
Gallus gallus
Q5ZIU3
526
59419
C126
V
I
G
G
P
N
N
C
G
Y
D
D
D
Q
G
Frog
Xenopus laevis
NP_001091432
462
54946
E126
R
S
V
E
D
D
E
E
G
H
L
I
C
E
S
Zebra Danio
Brachydanio rerio
NP_001038344
526
62655
S154
R
T
R
S
Y
S
A
S
S
S
R
S
D
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49762
832
95705
A446
Q
N
E
M
S
K
S
A
L
G
L
H
F
I
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
V126
E
R
K
E
M
V
A
V
K
I
V
R
G
V
K
Baker's Yeast
Sacchar. cerevisiae
P32350
737
83824
Q255
P
F
S
N
P
P
A
Q
I
A
S
L
P
Q
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.8
99.3
98.1
N.A.
97
52
N.A.
90.8
22
68.1
53.4
N.A.
31.8
N.A.
N.A.
N.A.
Protein Similarity:
100
91.4
99.7
99.1
N.A.
98.5
66.7
N.A.
94.1
39.1
78.5
68
N.A.
43.7
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
80
13.3
N.A.
13.3
0
6.6
33.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
100
N.A.
86.6
20
N.A.
20
13.3
13.3
40
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.7
26.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.2
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
0
24
8
0
8
0
0
0
0
8
% A
% Cys:
0
8
31
0
0
0
0
8
0
0
0
0
16
0
0
% C
% Asp:
0
0
0
0
16
16
0
0
8
0
8
8
16
0
0
% D
% Glu:
8
0
8
24
0
8
8
16
0
0
0
0
8
8
8
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
8
8
0
0
0
0
24
8
0
8
8
8
16
% G
% His:
8
24
0
0
8
31
0
8
8
16
0
16
31
0
0
% H
% Ile:
0
8
0
0
0
0
8
0
8
8
0
8
0
8
8
% I
% Lys:
0
0
8
0
0
8
8
0
8
0
31
0
0
0
16
% K
% Leu:
8
0
0
0
0
0
0
0
8
0
31
8
0
0
0
% L
% Met:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
0
8
8
0
0
0
0
0
0
0
0
% N
% Pro:
8
8
0
0
16
8
0
0
0
0
0
0
8
0
0
% P
% Gln:
8
0
0
0
0
8
31
8
0
0
0
0
0
16
0
% Q
% Arg:
54
16
8
8
0
0
0
0
24
8
8
8
8
47
31
% R
% Ser:
0
16
16
39
39
8
16
39
16
39
16
39
0
8
16
% S
% Thr:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% T
% Val:
8
0
16
0
0
8
0
16
0
0
8
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
16
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _