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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLSPN
All Species:
18.79
Human Site:
T493
Identified Species:
45.93
UniProt:
Q9HAW4
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAW4
NP_071394.2
1339
151094
T493
P
E
K
V
R
R
F
T
L
D
R
L
K
Q
L
Chimpanzee
Pan troglodytes
XP_001167189
1273
143970
T493
P
E
K
V
R
R
F
T
L
D
R
L
K
Q
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539598
1574
177075
T729
P
E
K
V
R
R
F
T
L
D
R
L
K
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80YR7
1315
146671
T499
P
E
K
V
R
R
F
T
V
D
R
L
R
Q
L
Rat
Rattus norvegicus
NP_001100157
1223
136693
P468
K
T
E
S
A
V
A
P
P
G
K
A
R
R
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510157
1511
167716
T663
P
P
K
V
R
K
F
T
R
D
K
L
Q
Q
L
Chicken
Gallus gallus
XP_425782
1387
154373
K548
P
E
K
V
R
K
S
K
L
D
K
L
R
E
L
Frog
Xenopus laevis
Q9DF50
1285
145963
K470
T
H
K
P
K
L
S
K
L
E
K
L
K
A
L
Zebra Danio
Brachydanio rerio
XP_002665647
920
101092
T172
P
R
P
K
R
E
R
T
L
Q
L
N
V
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121723
780
90984
L32
T
K
E
N
E
T
N
L
E
I
A
E
I
H
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.5
N.A.
72.4
N.A.
75.5
71.6
N.A.
55.9
51.7
46.2
33.9
N.A.
N.A.
20.6
N.A.
N.A.
Protein Similarity:
100
94.8
N.A.
77.4
N.A.
84.1
79
N.A.
66.7
66.9
63.4
46.1
N.A.
N.A.
36.1
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
86.6
0
N.A.
66.6
60
33.3
26.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
26.6
N.A.
86.6
86.6
53.3
26.6
N.A.
N.A.
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
10
0
0
0
10
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
60
0
0
0
0
0
% D
% Glu:
0
50
20
0
10
10
0
0
10
10
0
10
0
10
0
% E
% Phe:
0
0
0
0
0
0
50
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% I
% Lys:
10
10
70
10
10
20
0
20
0
0
40
0
40
0
0
% K
% Leu:
0
0
0
0
0
10
0
10
60
0
10
70
0
0
70
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
10
0
0
0
0
10
0
0
0
% N
% Pro:
70
10
10
10
0
0
0
10
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
10
50
0
% Q
% Arg:
0
10
0
0
70
40
10
0
10
0
40
0
30
10
10
% R
% Ser:
0
0
0
10
0
0
20
0
0
0
0
0
0
0
0
% S
% Thr:
20
10
0
0
0
10
0
60
0
0
0
0
0
0
0
% T
% Val:
0
0
0
60
0
10
0
0
10
0
0
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _