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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 31.52
Human Site: Y91 Identified Species: 57.78
UniProt: Q9HAU6 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HAU6 NP_003286 173 20263 Y91 T K E A Y K K Y I K D Y M K S
Chimpanzee Pan troglodytes XP_001146432 172 19563 Y91 T K E G Y K K Y I K D Y M K S
Rhesus Macaque Macaca mulatta XP_001112392 172 19576 Y91 T K E A Y K K Y I K D Y M K S
Dog Lupus familis XP_856393 133 15058 S64 P E G E G T E S T V I T G V D
Cat Felis silvestris
Mouse Mus musculus NP_033455 172 19444 Y91 T K E A Y K K Y I K D Y M K S
Rat Rattus norvegicus P63029 172 19444 Y91 T K E A Y K K Y I K D Y M K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P43347 172 19512 Y91 T K E S Y K K Y I K D Y M K A
Frog Xenopus laevis Q7ZYF2 172 19508 Y91 T K D S Y K N Y I K D Y V K Q
Zebra Danio Brachydanio rerio Q9DGK4 171 19006 I91 K K S Y T A Y I K D Y M K A V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VGS2 172 19619 K91 K S Y T L Y L K D Y M K K V L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays Q8H6A5 167 18672 Y89 D K K S F V S Y I K K Y I K N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P35691 167 18723 Y90 F L T Y I K G Y M K A V K A K
Red Bread Mold Neurospora crassa Q7RYV5 170 19009 M91 L V Y L K G Y M K S V K N A L
Conservation
Percent
Protein Identity: 100 72.2 72.2 58.3 N.A. 69.9 69.9 N.A. N.A. 66.4 52.5 49.7 N.A. 40.4 N.A. N.A. N.A.
Protein Similarity: 100 83.8 84.3 66.4 N.A. 83.2 83.2 N.A. N.A. 82 72.2 71.6 N.A. 65.3 N.A. N.A. N.A.
P-Site Identity: 100 93.3 100 0 N.A. 100 100 N.A. N.A. 86.6 66.6 6.6 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 93.3 100 13.3 N.A. 100 100 N.A. N.A. 100 86.6 6.6 N.A. 0 N.A. N.A. N.A.
Percent
Protein Identity: N.A. 36.4 N.A. N.A. 32.9 35.2
Protein Similarity: N.A. 55.4 N.A. N.A. 60.1 60.6
P-Site Identity: N.A. 40 N.A. N.A. 20 0
P-Site Similarity: N.A. 73.3 N.A. N.A. 26.6 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 31 0 8 0 0 0 0 8 0 0 24 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 8 0 0 0 0 0 8 8 54 0 0 0 8 % D
% Glu: 0 8 47 8 0 0 8 0 0 0 0 0 0 0 0 % E
% Phe: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 8 8 8 8 0 0 0 0 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 8 62 0 8 0 8 0 0 % I
% Lys: 16 70 8 0 8 62 47 8 16 70 8 16 24 62 8 % K
% Leu: 8 8 0 8 8 0 8 0 0 0 0 0 0 0 16 % L
% Met: 0 0 0 0 0 0 0 8 8 0 8 8 47 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 0 0 0 8 0 8 % N
% Pro: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 8 8 24 0 0 8 8 0 8 0 0 0 0 39 % S
% Thr: 54 0 8 8 8 8 0 0 8 0 0 8 0 0 0 % T
% Val: 0 8 0 0 0 8 0 0 0 8 8 8 8 16 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 16 16 54 8 16 70 0 8 8 62 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _