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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1B
All Species:
27.88
Human Site:
Y99
Identified Species:
43.81
UniProt:
Q9H9Y6
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Y6
NP_001131076.1
1135
128229
Y99
I
C
K
E
A
N
V
Y
P
A
E
C
R
G
R
Chimpanzee
Pan troglodytes
XP_515692
1135
128294
Y99
I
C
K
E
A
N
V
Y
P
A
E
C
R
G
R
Rhesus Macaque
Macaca mulatta
XP_001088474
1135
128257
Y99
I
C
K
E
V
S
V
Y
P
A
E
C
R
G
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P70700
1135
127957
Y99
I
C
K
D
L
N
V
Y
P
A
E
C
R
G
R
Rat
Rattus norvegicus
O54888
1135
127691
Y99
I
C
K
E
L
N
I
Y
P
A
E
C
R
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515678
1146
129549
F110
I
C
K
E
L
K
V
F
P
A
E
C
R
G
R
Chicken
Gallus gallus
XP_415007
1041
117633
L88
L
E
K
V
I
R
M
L
I
M
P
R
R
N
F
Frog
Xenopus laevis
NP_001080005
1134
128197
Y99
I
C
K
E
Q
K
I
Y
P
A
E
C
R
G
R
Zebra Danio
Brachydanio rerio
NP_956812
1132
127666
F98
I
S
R
D
L
R
V
F
P
A
E
C
R
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20028
1129
128426
Y98
D
V
R
T
R
E
I
Y
P
T
D
S
R
Q
L
Honey Bee
Apis mellifera
XP_001120416
1121
127333
Y91
G
I
K
T
H
K
I
Y
P
T
E
C
R
Q
R
Nematode Worm
Caenorhab. elegans
Q10578
1193
134886
A120
M
P
M
M
P
N
E
A
R
L
R
N
L
T
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38420
1188
135001
F111
D
G
E
T
A
T
L
F
P
K
A
A
R
L
R
Baker's Yeast
Sacchar. cerevisiae
P22138
1203
135723
Y122
S
A
V
E
R
K
V
Y
P
S
E
S
R
Q
R
Red Bread Mold
Neurospora crassa
O74633
1234
138583
F117
W
A
K
N
R
E
I
F
P
A
E
C
R
E
R
Conservation
Percent
Protein Identity:
100
99.5
98.6
N.A.
N.A.
89.6
85.2
N.A.
83.5
68.1
77
75.7
N.A.
45.2
47.1
28.3
N.A.
Protein Similarity:
100
99.8
99.5
N.A.
N.A.
95.4
90.3
N.A.
92.8
79.5
88.9
89.2
N.A.
64.9
66
44.9
N.A.
P-Site Identity:
100
100
86.6
N.A.
N.A.
86.6
86.6
N.A.
80
13.3
80
60
N.A.
20
46.6
6.6
N.A.
P-Site Similarity:
100
100
93.3
N.A.
N.A.
93.3
93.3
N.A.
86.6
26.6
86.6
80
N.A.
40
53.3
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
42.4
44
Protein Similarity:
N.A.
N.A.
N.A.
42.8
61.9
60.7
P-Site Identity:
N.A.
N.A.
N.A.
26.6
46.6
46.6
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
53.3
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
0
20
0
0
7
0
60
7
7
0
0
0
% A
% Cys:
0
47
0
0
0
0
0
0
0
0
0
67
0
0
0
% C
% Asp:
14
0
0
14
0
0
0
0
0
0
7
0
0
0
0
% D
% Glu:
0
7
7
47
0
14
7
0
0
0
74
0
0
7
0
% E
% Phe:
0
0
0
0
0
0
0
27
0
0
0
0
0
0
7
% F
% Gly:
7
7
0
0
0
0
0
0
0
0
0
0
0
54
0
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
54
7
0
0
7
0
34
0
7
0
0
0
0
0
0
% I
% Lys:
0
0
67
0
0
27
0
0
0
7
0
0
0
0
0
% K
% Leu:
7
0
0
0
27
0
7
7
0
7
0
0
7
7
7
% L
% Met:
7
0
7
7
0
0
7
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
34
0
0
0
0
0
7
0
7
0
% N
% Pro:
0
7
0
0
7
0
0
0
87
0
7
0
0
0
0
% P
% Gln:
0
0
0
0
7
0
0
0
0
0
0
0
0
20
0
% Q
% Arg:
0
0
14
0
20
14
0
0
7
0
7
7
94
0
80
% R
% Ser:
7
7
0
0
0
7
0
0
0
7
0
14
0
0
0
% S
% Thr:
0
0
0
20
0
7
0
0
0
14
0
0
0
7
0
% T
% Val:
0
7
7
7
7
0
47
0
0
0
0
0
0
0
0
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
60
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _