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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1B
All Species:
36.67
Human Site:
Y841
Identified Species:
57.62
UniProt:
Q9H9Y6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Y6
NP_001131076.1
1135
128229
Y841
G
E
S
F
V
M
Y
Y
K
S
K
E
N
C
V
Chimpanzee
Pan troglodytes
XP_515692
1135
128294
Y841
G
E
S
F
V
M
Y
Y
K
S
K
E
N
C
V
Rhesus Macaque
Macaca mulatta
XP_001088474
1135
128257
Y841
G
E
S
F
V
M
Y
Y
K
S
K
E
N
C
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P70700
1135
127957
Y841
G
E
G
F
V
V
Y
Y
K
S
K
E
N
C
V
Rat
Rattus norvegicus
O54888
1135
127691
Y841
G
E
G
F
V
V
Y
Y
K
S
K
E
N
C
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515678
1146
129549
Y852
G
E
S
F
V
T
Y
Y
K
S
K
E
D
C
V
Chicken
Gallus gallus
XP_415007
1041
117633
Y747
G
E
T
F
T
V
Y
Y
Q
N
K
E
V
G
I
Frog
Xenopus laevis
NP_001080005
1134
128197
Y840
G
E
S
F
V
A
Y
Y
K
S
K
E
N
C
V
Zebra Danio
Brachydanio rerio
NP_956812
1132
127666
Y838
G
Q
S
H
V
Y
F
Y
K
Y
Q
E
S
C
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20028
1129
128426
K832
V
A
T
Y
K
V
V
K
M
D
E
K
E
D
C
Honey Bee
Apis mellifera
XP_001120416
1121
127333
K827
Q
S
T
Y
I
T
G
K
Y
H
G
K
E
D
A
Nematode Worm
Caenorhab. elegans
Q10578
1193
134886
S899
K
Y
P
K
R
D
A
S
T
F
L
R
S
S
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38420
1188
135001
S899
R
Y
T
R
R
D
H
S
I
S
L
R
H
S
E
Baker's Yeast
Sacchar. cerevisiae
P22138
1203
135723
H875
K
T
K
I
K
T
Y
H
S
S
E
P
A
Y
I
Red Bread Mold
Neurospora crassa
O74633
1234
138583
Y890
G
V
T
H
Y
E
R
Y
K
D
S
E
D
A
F
Conservation
Percent
Protein Identity:
100
99.5
98.6
N.A.
N.A.
89.6
85.2
N.A.
83.5
68.1
77
75.7
N.A.
45.2
47.1
28.3
N.A.
Protein Similarity:
100
99.8
99.5
N.A.
N.A.
95.4
90.3
N.A.
92.8
79.5
88.9
89.2
N.A.
64.9
66
44.9
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
86.6
86.6
N.A.
86.6
46.6
93.3
53.3
N.A.
0
0
0
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
93.3
N.A.
93.3
80
93.3
80
N.A.
33.3
26.6
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
42.4
44
Protein Similarity:
N.A.
N.A.
N.A.
42.8
61.9
60.7
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
7
7
0
0
0
0
0
7
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
54
7
% C
% Asp:
0
0
0
0
0
14
0
0
0
14
0
0
14
14
0
% D
% Glu:
0
54
0
0
0
7
0
0
0
0
14
67
14
0
14
% E
% Phe:
0
0
0
54
0
0
7
0
0
7
0
0
0
0
7
% F
% Gly:
67
0
14
0
0
0
7
0
0
0
7
0
0
7
0
% G
% His:
0
0
0
14
0
0
7
7
0
7
0
0
7
0
0
% H
% Ile:
0
0
0
7
7
0
0
0
7
0
0
0
0
0
14
% I
% Lys:
14
0
7
7
14
0
0
14
60
0
54
14
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
14
0
0
0
0
% L
% Met:
0
0
0
0
0
20
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
7
0
0
40
0
0
% N
% Pro:
0
0
7
0
0
0
0
0
0
0
0
7
0
0
0
% P
% Gln:
7
7
0
0
0
0
0
0
7
0
7
0
0
0
0
% Q
% Arg:
7
0
0
7
14
0
7
0
0
0
0
14
0
0
0
% R
% Ser:
0
7
40
0
0
0
0
14
7
60
7
0
14
14
0
% S
% Thr:
0
7
34
0
7
20
0
0
7
0
0
0
0
0
0
% T
% Val:
7
7
0
0
54
27
7
0
0
0
0
0
7
0
54
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
14
0
14
7
7
60
67
7
7
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _