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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1B
All Species:
22.12
Human Site:
Y825
Identified Species:
34.76
UniProt:
Q9H9Y6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Y6
NP_001131076.1
1135
128229
Y825
K
L
Q
Y
G
D
P
Y
Y
S
Y
L
N
L
N
Chimpanzee
Pan troglodytes
XP_515692
1135
128294
Y825
K
L
Q
Y
G
D
P
Y
Y
S
Y
L
N
L
N
Rhesus Macaque
Macaca mulatta
XP_001088474
1135
128257
Y825
K
L
Q
Y
G
D
P
Y
Y
S
Y
L
N
L
N
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P70700
1135
127957
Y825
K
L
E
Y
G
D
P
Y
Y
S
Y
L
N
L
N
Rat
Rattus norvegicus
O54888
1135
127691
Y825
K
L
E
F
G
D
P
Y
Y
G
Y
L
N
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515678
1146
129549
F836
V
L
Q
Y
G
D
P
F
Y
S
Y
V
N
L
N
Chicken
Gallus gallus
XP_415007
1041
117633
F731
I
L
Q
P
G
D
P
F
Y
S
Y
M
N
L
N
Frog
Xenopus laevis
NP_001080005
1134
128197
Y824
V
L
Q
F
G
D
P
Y
Y
G
Y
L
N
F
N
Zebra Danio
Brachydanio rerio
NP_956812
1132
127666
F822
V
L
K
Y
G
D
P
F
Y
G
Y
I
S
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20028
1129
128426
P816
S
K
L
S
Y
G
S
P
L
Y
C
Y
F
D
G
Honey Bee
Apis mellifera
XP_001120416
1121
127333
V811
T
I
I
S
E
G
D
V
Y
Y
C
Y
Y
D
A
Nematode Worm
Caenorhab. elegans
Q10578
1193
134886
D883
T
V
A
L
P
D
I
D
D
D
L
D
A
S
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38420
1188
135001
Q883
G
K
T
T
P
I
S
Q
D
E
A
Q
G
Q
S
Baker's Yeast
Sacchar. cerevisiae
P22138
1203
135723
C859
V
E
E
G
D
P
I
C
A
Y
F
D
D
T
L
Red Bread Mold
Neurospora crassa
O74633
1234
138583
Y874
W
H
T
V
S
A
D
Y
N
G
Q
L
V
N
R
Conservation
Percent
Protein Identity:
100
99.5
98.6
N.A.
N.A.
89.6
85.2
N.A.
83.5
68.1
77
75.7
N.A.
45.2
47.1
28.3
N.A.
Protein Similarity:
100
99.8
99.5
N.A.
N.A.
95.4
90.3
N.A.
92.8
79.5
88.9
89.2
N.A.
64.9
66
44.9
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
93.3
80
N.A.
80
73.3
73.3
60
N.A.
0
6.6
6.6
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
100
93.3
N.A.
93.3
86.6
80
86.6
N.A.
0
13.3
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
42.4
44
Protein Similarity:
N.A.
N.A.
N.A.
42.8
61.9
60.7
P-Site Identity:
N.A.
N.A.
N.A.
0
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
7
0
0
7
0
7
0
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
14
0
0
0
0
% C
% Asp:
0
0
0
0
7
67
14
7
14
7
0
14
7
14
0
% D
% Glu:
0
7
20
0
7
0
0
0
0
7
0
0
0
0
0
% E
% Phe:
0
0
0
14
0
0
0
20
0
0
7
0
7
7
0
% F
% Gly:
7
0
0
7
60
14
0
0
0
27
0
0
7
0
14
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
7
7
0
0
7
14
0
0
0
0
7
0
0
0
% I
% Lys:
34
14
7
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
60
7
7
0
0
0
0
7
0
7
47
0
54
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
7
0
0
0
54
7
60
% N
% Pro:
0
0
0
7
14
7
60
7
0
0
0
0
0
0
0
% P
% Gln:
0
0
40
0
0
0
0
7
0
0
7
7
0
7
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% R
% Ser:
7
0
0
14
7
0
14
0
0
40
0
0
7
7
7
% S
% Thr:
14
0
14
7
0
0
0
0
0
0
0
0
0
7
0
% T
% Val:
27
7
0
7
0
0
0
7
0
0
0
7
7
0
0
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
40
7
0
0
47
67
20
60
14
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _