KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1B
All Species:
49.39
Human Site:
Y712
Identified Species:
77.62
UniProt:
Q9H9Y6
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Y6
NP_001131076.1
1135
128229
Y712
D
R
S
D
N
K
L
Y
R
L
Q
T
P
Q
S
Chimpanzee
Pan troglodytes
XP_515692
1135
128294
Y712
D
R
S
D
N
K
L
Y
R
L
Q
T
P
Q
S
Rhesus Macaque
Macaca mulatta
XP_001088474
1135
128257
Y712
D
R
S
D
N
K
L
Y
R
L
Q
T
P
Q
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P70700
1135
127957
Y712
N
R
S
D
N
K
L
Y
R
L
Q
T
P
Q
S
Rat
Rattus norvegicus
O54888
1135
127691
Y712
D
R
S
D
N
K
L
Y
R
L
Q
T
P
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515678
1146
129549
Y723
E
R
S
D
N
K
L
Y
R
L
H
S
P
Q
S
Chicken
Gallus gallus
XP_415007
1041
117633
Y633
P
L
V
R
P
R
M
Y
D
Y
Y
G
M
D
S
Frog
Xenopus laevis
NP_001080005
1134
128197
Y711
D
R
S
D
N
K
L
Y
R
L
Q
T
P
Q
S
Zebra Danio
Brachydanio rerio
NP_956812
1132
127666
Y710
Y
R
S
D
N
K
L
Y
R
L
Q
T
P
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20028
1129
128426
Y710
K
Q
A
A
N
K
L
Y
R
L
Q
T
P
G
T
Honey Bee
Apis mellifera
XP_001120416
1121
127333
Y705
L
Q
S
E
T
K
L
Y
R
L
Q
T
P
A
T
Nematode Worm
Caenorhab. elegans
Q10578
1193
134886
H755
V
R
M
D
T
L
A
H
V
L
Y
Y
P
Q
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38420
1188
135001
Y757
F
R
M
D
T
L
A
Y
V
L
Y
Y
P
Q
K
Baker's Yeast
Sacchar. cerevisiae
P22138
1203
135723
Y742
H
R
S
D
N
K
L
Y
R
L
Q
T
G
Q
T
Red Bread Mold
Neurospora crassa
O74633
1234
138583
Y745
H
R
T
D
N
K
M
Y
R
L
Q
T
G
Q
T
Conservation
Percent
Protein Identity:
100
99.5
98.6
N.A.
N.A.
89.6
85.2
N.A.
83.5
68.1
77
75.7
N.A.
45.2
47.1
28.3
N.A.
Protein Similarity:
100
99.8
99.5
N.A.
N.A.
95.4
90.3
N.A.
92.8
79.5
88.9
89.2
N.A.
64.9
66
44.9
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
93.3
100
N.A.
80
13.3
100
93.3
N.A.
60
60
33.3
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
93.3
26.6
100
93.3
N.A.
80
80
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
42.4
44
Protein Similarity:
N.A.
N.A.
N.A.
42.8
61.9
60.7
P-Site Identity:
N.A.
N.A.
N.A.
40
80
66.6
P-Site Similarity:
N.A.
N.A.
N.A.
40
86.6
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
7
0
0
14
0
0
0
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
34
0
0
80
0
0
0
0
7
0
0
0
0
7
0
% D
% Glu:
7
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
7
14
7
0
% G
% His:
14
0
0
0
0
0
0
7
0
0
7
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
7
0
0
0
0
80
0
0
0
0
0
0
0
0
14
% K
% Leu:
7
7
0
0
0
14
74
0
0
94
0
0
0
0
0
% L
% Met:
0
0
14
0
0
0
14
0
0
0
0
0
7
0
0
% M
% Asn:
7
0
0
0
74
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
7
0
0
0
7
0
0
0
0
0
0
0
80
0
0
% P
% Gln:
0
14
0
0
0
0
0
0
0
0
74
0
0
80
0
% Q
% Arg:
0
80
0
7
0
7
0
0
80
0
0
0
0
0
0
% R
% Ser:
0
0
67
0
0
0
0
0
0
0
0
7
0
0
60
% S
% Thr:
0
0
7
0
20
0
0
0
0
0
0
74
0
0
27
% T
% Val:
7
0
7
0
0
0
0
0
14
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
94
0
7
20
14
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _