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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1B
All Species:
43.33
Human Site:
Y110
Identified Species:
68.1
UniProt:
Q9H9Y6
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Y6
NP_001131076.1
1135
128229
Y110
C
R
G
R
R
S
T
Y
R
G
K
L
T
A
D
Chimpanzee
Pan troglodytes
XP_515692
1135
128294
Y110
C
R
G
R
R
S
T
Y
R
G
K
L
T
A
D
Rhesus Macaque
Macaca mulatta
XP_001088474
1135
128257
Y110
C
R
G
R
R
S
T
Y
R
G
K
L
T
A
D
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P70700
1135
127957
Y110
C
R
G
R
K
S
T
Y
R
G
R
L
T
A
D
Rat
Rattus norvegicus
O54888
1135
127691
Y110
C
R
G
R
R
S
T
Y
R
G
K
L
T
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515678
1146
129549
Y121
C
R
G
R
R
S
T
Y
R
G
K
L
T
A
D
Chicken
Gallus gallus
XP_415007
1041
117633
M99
R
R
N
F
P
L
A
M
T
R
H
K
W
K
N
Frog
Xenopus laevis
NP_001080005
1134
128197
Y110
C
R
G
R
R
S
T
Y
R
G
K
L
T
A
D
Zebra Danio
Brachydanio rerio
NP_956812
1132
127666
Y109
C
R
G
R
R
C
T
Y
R
A
K
L
V
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20028
1129
128426
Y109
S
R
Q
L
H
V
S
Y
S
G
M
C
S
V
R
Honey Bee
Apis mellifera
XP_001120416
1121
127333
Y102
C
R
Q
R
G
C
S
Y
K
G
K
I
T
V
K
Nematode Worm
Caenorhab. elegans
Q10578
1193
134886
L131
N
L
T
Y
A
S
P
L
Y
V
D
I
T
K
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38420
1188
135001
Y122
A
R
L
R
N
L
T
Y
S
A
P
L
Y
V
D
Baker's Yeast
Sacchar. cerevisiae
P22138
1203
135723
Y133
S
R
Q
R
L
T
S
Y
R
G
K
L
L
L
K
Red Bread Mold
Neurospora crassa
O74633
1234
138583
Y128
C
R
E
R
H
V
S
Y
R
G
K
L
S
A
T
Conservation
Percent
Protein Identity:
100
99.5
98.6
N.A.
N.A.
89.6
85.2
N.A.
83.5
68.1
77
75.7
N.A.
45.2
47.1
28.3
N.A.
Protein Similarity:
100
99.8
99.5
N.A.
N.A.
95.4
90.3
N.A.
92.8
79.5
88.9
89.2
N.A.
64.9
66
44.9
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
86.6
100
N.A.
100
6.6
100
80
N.A.
20
46.6
13.3
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
100
13.3
100
80
N.A.
33.3
66.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
42.4
44
Protein Similarity:
N.A.
N.A.
N.A.
42.8
61.9
60.7
P-Site Identity:
N.A.
N.A.
N.A.
40
46.6
60
P-Site Similarity:
N.A.
N.A.
N.A.
40
60
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
7
0
7
0
0
14
0
0
0
60
0
% A
% Cys:
67
0
0
0
0
14
0
0
0
0
0
7
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
60
% D
% Glu:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
54
0
7
0
0
0
0
74
0
0
0
0
0
% G
% His:
0
0
0
0
14
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
14
0
0
0
% I
% Lys:
0
0
0
0
7
0
0
0
7
0
67
7
0
14
14
% K
% Leu:
0
7
7
7
7
14
0
7
0
0
0
74
7
7
0
% L
% Met:
0
0
0
0
0
0
0
7
0
0
7
0
0
0
0
% M
% Asn:
7
0
7
0
7
0
0
0
0
0
0
0
0
0
7
% N
% Pro:
0
0
0
0
7
0
7
0
0
0
7
0
0
0
0
% P
% Gln:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
94
0
80
47
0
0
0
67
7
7
0
0
0
7
% R
% Ser:
14
0
0
0
0
54
27
0
14
0
0
0
14
0
0
% S
% Thr:
0
0
7
0
0
7
60
0
7
0
0
0
60
0
7
% T
% Val:
0
0
0
0
0
14
0
0
0
7
0
0
7
20
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
0
7
0
0
0
87
7
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _