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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1B
All Species:
29.7
Human Site:
T296
Identified Species:
46.67
UniProt:
Q9H9Y6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Y6
NP_001131076.1
1135
128229
T296
V
M
E
E
G
C
S
T
Q
K
Q
V
L
N
Y
Chimpanzee
Pan troglodytes
XP_515692
1135
128294
T296
V
M
E
E
G
C
L
T
Q
K
Q
V
L
N
Y
Rhesus Macaque
Macaca mulatta
XP_001088474
1135
128257
T296
V
M
E
E
G
C
S
T
Q
K
Q
V
L
N
Y
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P70700
1135
127957
S296
V
I
E
E
G
C
H
S
Q
K
Q
V
L
N
Y
Rat
Rattus norvegicus
O54888
1135
127691
T296
V
M
E
E
G
C
H
T
Q
K
Q
V
L
D
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515678
1146
129549
T307
V
M
E
E
G
C
T
T
Q
K
Q
V
L
N
Y
Chicken
Gallus gallus
XP_415007
1041
117633
R257
Y
L
L
C
M
M
T
R
K
L
C
A
F
A
K
Frog
Xenopus laevis
NP_001080005
1134
128197
N296
V
V
E
E
G
C
H
N
Q
K
N
V
L
K
Y
Zebra Danio
Brachydanio rerio
NP_956812
1132
127666
T295
V
M
D
Q
G
C
T
T
K
I
K
V
L
N
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20028
1129
128426
T295
V
Q
N
E
N
V
Y
T
H
A
Q
C
K
S
F
Honey Bee
Apis mellifera
XP_001120416
1121
127333
N288
V
H
E
Q
G
L
N
N
H
E
E
C
K
A
Y
Nematode Worm
Caenorhab. elegans
Q10578
1193
134886
I317
S
L
D
E
A
F
V
I
Q
E
Q
N
V
A
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38420
1188
135001
I316
S
L
E
E
A
F
V
I
Q
N
Q
L
V
A
L
Baker's Yeast
Sacchar. cerevisiae
P22138
1203
135723
L320
F
K
K
R
Y
P
H
L
Q
N
R
T
Q
V
L
Red Bread Mold
Neurospora crassa
O74633
1234
138583
S318
Y
K
K
Y
G
L
Y
S
K
T
Q
T
R
A
Y
Conservation
Percent
Protein Identity:
100
99.5
98.6
N.A.
N.A.
89.6
85.2
N.A.
83.5
68.1
77
75.7
N.A.
45.2
47.1
28.3
N.A.
Protein Similarity:
100
99.8
99.5
N.A.
N.A.
95.4
90.3
N.A.
92.8
79.5
88.9
89.2
N.A.
64.9
66
44.9
N.A.
P-Site Identity:
100
93.3
100
N.A.
N.A.
80
86.6
N.A.
93.3
0
66.6
60
N.A.
26.6
26.6
20
N.A.
P-Site Similarity:
100
93.3
100
N.A.
N.A.
93.3
93.3
N.A.
100
20
73.3
93.3
N.A.
40
53.3
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
42.4
44
Protein Similarity:
N.A.
N.A.
N.A.
42.8
61.9
60.7
P-Site Identity:
N.A.
N.A.
N.A.
26.6
6.6
20
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
20
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
14
0
0
0
0
7
0
7
0
34
0
% A
% Cys:
0
0
0
7
0
54
0
0
0
0
7
14
0
0
0
% C
% Asp:
0
0
14
0
0
0
0
0
0
0
0
0
0
7
0
% D
% Glu:
0
0
60
67
0
0
0
0
0
14
7
0
0
0
0
% E
% Phe:
7
0
0
0
0
14
0
0
0
0
0
0
7
0
7
% F
% Gly:
0
0
0
0
67
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
7
0
0
0
0
27
0
14
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
14
0
7
0
0
0
0
0
% I
% Lys:
0
14
14
0
0
0
0
0
20
47
7
0
14
7
7
% K
% Leu:
0
20
7
0
0
14
7
7
0
7
0
7
54
0
20
% L
% Met:
0
40
0
0
7
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
7
0
7
14
0
14
7
7
0
40
0
% N
% Pro:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
14
0
0
0
0
67
0
67
0
7
0
0
% Q
% Arg:
0
0
0
7
0
0
0
7
0
0
7
0
7
0
0
% R
% Ser:
14
0
0
0
0
0
14
14
0
0
0
0
0
7
0
% S
% Thr:
0
0
0
0
0
0
20
47
0
7
0
14
0
0
0
% T
% Val:
67
7
0
0
0
7
14
0
0
0
0
54
14
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
14
0
0
7
7
0
14
0
0
0
0
0
0
0
67
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _