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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1B
All Species:
21.82
Human Site:
T1099
Identified Species:
34.29
UniProt:
Q9H9Y6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Y6
NP_001131076.1
1135
128229
T1099
R
N
R
K
Y
N
C
T
L
C
S
R
S
D
T
Chimpanzee
Pan troglodytes
XP_515692
1135
128294
T1099
R
N
R
K
Y
N
C
T
L
C
N
R
S
D
T
Rhesus Macaque
Macaca mulatta
XP_001088474
1135
128257
T1099
R
N
R
K
Y
N
C
T
L
C
N
R
S
D
T
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P70700
1135
127957
T1099
R
N
R
K
Y
N
C
T
V
C
G
R
S
D
T
Rat
Rattus norvegicus
O54888
1135
127691
T1099
R
N
R
K
Y
N
C
T
V
C
G
R
S
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515678
1146
129549
T1110
R
N
R
K
Y
N
C
T
V
C
R
Q
S
D
T
Chicken
Gallus gallus
XP_415007
1041
117633
L1005
S
R
R
Y
S
C
M
L
C
G
R
M
D
T
I
Frog
Xenopus laevis
NP_001080005
1134
128197
V1098
R
N
R
K
H
Q
C
V
V
C
N
R
T
D
T
Zebra Danio
Brachydanio rerio
NP_956812
1132
127666
L1096
R
H
R
K
T
I
C
L
L
C
N
K
S
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20028
1129
128426
C1090
L
S
S
Q
P
D
T
C
R
L
C
G
D
N
S
Honey Bee
Apis mellifera
XP_001120416
1121
127333
C1085
N
K
L
R
C
R
L
C
G
D
N
E
S
V
R
Nematode Worm
Caenorhab. elegans
Q10578
1193
134886
A1154
R
N
K
T
Q
V
S
A
V
R
I
P
Y
A
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38420
1188
135001
Q1153
K
N
K
T
D
I
V
Q
V
Y
I
P
Y
A
C
Baker's Yeast
Sacchar. cerevisiae
P22138
1203
135723
M1133
V
C
C
R
R
C
S
M
R
F
E
D
A
K
K
Red Bread Mold
Neurospora crassa
O74633
1234
138583
R1148
A
V
S
T
V
R
C
R
N
C
A
V
R
L
D
Conservation
Percent
Protein Identity:
100
99.5
98.6
N.A.
N.A.
89.6
85.2
N.A.
83.5
68.1
77
75.7
N.A.
45.2
47.1
28.3
N.A.
Protein Similarity:
100
99.8
99.5
N.A.
N.A.
95.4
90.3
N.A.
92.8
79.5
88.9
89.2
N.A.
64.9
66
44.9
N.A.
P-Site Identity:
100
93.3
93.3
N.A.
N.A.
86.6
80
N.A.
80
6.6
60
53.3
N.A.
0
6.6
13.3
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
93.3
N.A.
93.3
6.6
86.6
80
N.A.
33.3
20
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
42.4
44
Protein Similarity:
N.A.
N.A.
N.A.
42.8
61.9
60.7
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
0
7
0
0
7
0
7
14
0
% A
% Cys:
0
7
7
0
7
14
60
14
7
60
7
0
0
0
14
% C
% Asp:
0
0
0
0
7
7
0
0
0
7
0
7
14
54
7
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
7
7
14
7
0
0
0
% G
% His:
0
7
0
0
7
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
14
0
0
0
0
14
0
0
0
7
% I
% Lys:
7
7
14
54
0
0
0
0
0
0
0
7
0
7
7
% K
% Leu:
7
0
7
0
0
0
7
14
27
7
0
0
0
7
0
% L
% Met:
0
0
0
0
0
0
7
7
0
0
0
7
0
0
0
% M
% Asn:
7
60
0
0
0
40
0
0
7
0
34
0
0
7
0
% N
% Pro:
0
0
0
0
7
0
0
0
0
0
0
14
0
0
0
% P
% Gln:
0
0
0
7
7
7
0
7
0
0
0
7
0
0
0
% Q
% Arg:
60
7
60
14
7
14
0
7
14
7
14
40
7
0
7
% R
% Ser:
7
7
14
0
7
0
14
0
0
0
7
0
54
0
20
% S
% Thr:
0
0
0
20
7
0
7
40
0
0
0
0
7
7
40
% T
% Val:
7
7
0
0
7
7
7
7
40
0
0
7
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
40
0
0
0
0
7
0
0
14
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _