KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1B
All Species:
30
Human Site:
S836
Identified Species:
47.14
UniProt:
Q9H9Y6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Y6
NP_001131076.1
1135
128229
S836
L
N
L
N
T
G
E
S
F
V
M
Y
Y
K
S
Chimpanzee
Pan troglodytes
XP_515692
1135
128294
S836
L
N
L
N
T
G
E
S
F
V
M
Y
Y
K
S
Rhesus Macaque
Macaca mulatta
XP_001088474
1135
128257
S836
L
N
L
N
T
G
E
S
F
V
M
Y
Y
K
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P70700
1135
127957
G836
L
N
L
N
T
G
E
G
F
V
V
Y
Y
K
S
Rat
Rattus norvegicus
O54888
1135
127691
G836
L
N
L
N
T
G
E
G
F
V
V
Y
Y
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515678
1146
129549
S847
V
N
L
N
T
G
E
S
F
V
T
Y
Y
K
S
Chicken
Gallus gallus
XP_415007
1041
117633
T742
M
N
L
N
T
G
E
T
F
T
V
Y
Y
Q
N
Frog
Xenopus laevis
NP_001080005
1134
128197
S835
L
N
F
N
T
G
E
S
F
V
A
Y
Y
K
S
Zebra Danio
Brachydanio rerio
NP_956812
1132
127666
S833
I
S
L
N
T
G
Q
S
H
V
Y
F
Y
K
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20028
1129
128426
T827
Y
F
D
G
E
V
A
T
Y
K
V
V
K
M
D
Honey Bee
Apis mellifera
XP_001120416
1121
127333
T822
Y
Y
D
A
D
Q
S
T
Y
I
T
G
K
Y
H
Nematode Worm
Caenorhab. elegans
Q10578
1193
134886
P894
D
A
S
G
K
K
Y
P
K
R
D
A
S
T
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38420
1188
135001
T894
Q
G
Q
S
S
R
Y
T
R
R
D
H
S
I
S
Baker's Yeast
Sacchar. cerevisiae
P22138
1203
135723
K870
D
D
T
L
N
K
T
K
I
K
T
Y
H
S
S
Red Bread Mold
Neurospora crassa
O74633
1234
138583
T885
L
V
N
R
D
G
V
T
H
Y
E
R
Y
K
D
Conservation
Percent
Protein Identity:
100
99.5
98.6
N.A.
N.A.
89.6
85.2
N.A.
83.5
68.1
77
75.7
N.A.
45.2
47.1
28.3
N.A.
Protein Similarity:
100
99.8
99.5
N.A.
N.A.
95.4
90.3
N.A.
92.8
79.5
88.9
89.2
N.A.
64.9
66
44.9
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
86.6
86.6
N.A.
86.6
60
86.6
53.3
N.A.
0
0
0
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
93.3
N.A.
93.3
93.3
86.6
80
N.A.
20
20
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
42.4
44
Protein Similarity:
N.A.
N.A.
N.A.
42.8
61.9
60.7
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
0
0
7
0
0
0
7
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
7
14
0
14
0
0
0
0
0
14
0
0
0
14
% D
% Glu:
0
0
0
0
7
0
54
0
0
0
7
0
0
0
0
% E
% Phe:
0
7
7
0
0
0
0
0
54
0
0
7
0
0
7
% F
% Gly:
0
7
0
14
0
67
0
14
0
0
0
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
14
0
0
7
7
0
7
% H
% Ile:
7
0
0
0
0
0
0
0
7
7
0
0
0
7
0
% I
% Lys:
0
0
0
0
7
14
0
7
7
14
0
0
14
60
0
% K
% Leu:
47
0
54
7
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
7
0
0
0
0
0
0
0
0
0
20
0
0
7
0
% M
% Asn:
0
54
7
60
7
0
0
0
0
0
0
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
7
0
7
0
0
7
7
0
0
0
0
0
0
7
0
% Q
% Arg:
0
0
0
7
0
7
0
0
7
14
0
7
0
0
0
% R
% Ser:
0
7
7
7
7
0
7
40
0
0
0
0
14
7
60
% S
% Thr:
0
0
7
0
60
0
7
34
0
7
20
0
0
7
0
% T
% Val:
7
7
0
0
0
7
7
0
0
54
27
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
14
7
0
0
0
0
14
0
14
7
7
60
67
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _