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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1B
All Species:
13.03
Human Site:
S791
Identified Species:
20.48
UniProt:
Q9H9Y6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Y6
NP_001131076.1
1135
128229
S791
K
I
K
Q
G
D
S
S
L
V
F
G
I
K
P
Chimpanzee
Pan troglodytes
XP_515692
1135
128294
S791
K
I
K
Q
G
D
S
S
L
V
F
G
I
K
P
Rhesus Macaque
Macaca mulatta
XP_001088474
1135
128257
S791
K
I
K
Q
G
D
S
S
L
V
F
G
I
K
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P70700
1135
127957
N791
K
F
K
Q
G
E
D
N
L
V
F
G
V
K
P
Rat
Rattus norvegicus
O54888
1135
127691
S791
K
F
K
Q
G
D
D
S
L
V
F
G
V
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515678
1146
129549
C802
K
I
K
Q
G
D
D
C
L
V
F
G
V
K
P
Chicken
Gallus gallus
XP_415007
1041
117633
K712
G
D
P
N
V
K
E
K
L
D
A
D
G
L
P
Frog
Xenopus laevis
NP_001080005
1134
128197
N790
K
L
K
D
G
E
D
N
I
V
F
G
I
K
P
Zebra Danio
Brachydanio rerio
NP_956812
1132
127666
I789
K
V
K
G
D
D
S
I
V
F
G
V
K
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20028
1129
128426
H789
K
S
S
Y
F
A
R
H
P
H
M
P
E
L
I
Honey Bee
Apis mellifera
XP_001120416
1121
127333
N784
Q
K
S
Y
F
A
R
N
P
D
K
S
E
L
V
Nematode Worm
Caenorhab. elegans
Q10578
1193
134886
L834
L
D
N
A
N
E
E
L
I
E
K
P
T
R
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38420
1188
135001
D836
M
G
T
L
V
K
E
D
F
G
R
P
D
R
G
Baker's Yeast
Sacchar. cerevisiae
P22138
1203
135723
I821
N
R
N
R
G
D
P
I
T
Q
H
F
G
F
G
Red Bread Mold
Neurospora crassa
O74633
1234
138583
K824
D
S
R
T
R
S
A
K
S
I
V
K
M
F
G
Conservation
Percent
Protein Identity:
100
99.5
98.6
N.A.
N.A.
89.6
85.2
N.A.
83.5
68.1
77
75.7
N.A.
45.2
47.1
28.3
N.A.
Protein Similarity:
100
99.8
99.5
N.A.
N.A.
95.4
90.3
N.A.
92.8
79.5
88.9
89.2
N.A.
64.9
66
44.9
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
66.6
80
N.A.
80
13.3
60
26.6
N.A.
6.6
0
0
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
86.6
86.6
N.A.
86.6
13.3
86.6
40
N.A.
6.6
13.3
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
42.4
44
Protein Similarity:
N.A.
N.A.
N.A.
42.8
61.9
60.7
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
14
7
0
0
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
7
14
0
7
7
47
27
7
0
14
0
7
7
0
0
% D
% Glu:
0
0
0
0
0
20
20
0
0
7
0
0
14
0
7
% E
% Phe:
0
14
0
0
14
0
0
0
7
7
47
7
0
14
0
% F
% Gly:
7
7
0
7
54
0
0
0
0
7
7
47
14
0
27
% G
% His:
0
0
0
0
0
0
0
7
0
7
7
0
0
0
0
% H
% Ile:
0
27
0
0
0
0
0
14
14
7
0
0
27
0
7
% I
% Lys:
60
7
54
0
0
14
0
14
0
0
14
7
7
47
0
% K
% Leu:
7
7
0
7
0
0
0
7
47
0
0
0
0
20
0
% L
% Met:
7
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% M
% Asn:
7
0
14
7
7
0
0
20
0
0
0
0
0
0
0
% N
% Pro:
0
0
7
0
0
0
7
0
14
0
0
20
0
7
54
% P
% Gln:
7
0
0
40
0
0
0
0
0
7
0
0
0
0
0
% Q
% Arg:
0
7
7
7
7
0
14
0
0
0
7
0
0
14
0
% R
% Ser:
0
14
14
0
0
7
27
27
7
0
0
7
0
0
0
% S
% Thr:
0
0
7
7
0
0
0
0
7
0
0
0
7
0
0
% T
% Val:
0
7
0
0
14
0
0
0
7
47
7
7
20
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
14
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _