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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1B
All Species:
33.33
Human Site:
S276
Identified Species:
52.38
UniProt:
Q9H9Y6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Y6
NP_001131076.1
1135
128229
S276
I
K
G
K
E
D
D
S
F
L
R
N
S
V
S
Chimpanzee
Pan troglodytes
XP_515692
1135
128294
S276
I
K
G
K
E
D
D
S
F
L
R
N
S
V
S
Rhesus Macaque
Macaca mulatta
XP_001088474
1135
128257
S276
I
K
G
K
E
D
D
S
F
L
R
N
S
V
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P70700
1135
127957
S276
I
K
G
K
E
E
D
S
F
F
R
N
S
V
S
Rat
Rattus norvegicus
O54888
1135
127691
S276
I
K
G
K
E
E
D
S
F
F
K
N
S
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515678
1146
129549
S287
I
K
G
R
E
D
N
S
F
Y
K
N
C
V
S
Chicken
Gallus gallus
XP_415007
1041
117633
C237
A
D
F
I
F
N
K
C
I
C
I
H
L
T
D
Frog
Xenopus laevis
NP_001080005
1134
128197
S276
I
K
G
K
E
D
N
S
F
Y
R
D
C
M
T
Zebra Danio
Brachydanio rerio
NP_956812
1132
127666
S275
I
K
G
R
E
D
N
S
F
Y
K
S
C
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20028
1129
128426
Q275
V
Q
G
Y
E
S
D
Q
Y
Y
V
S
C
V
Q
Honey Bee
Apis mellifera
XP_001120416
1121
127333
L268
T
A
G
C
E
Y
D
L
Y
Y
K
G
C
I
L
Nematode Worm
Caenorhab. elegans
Q10578
1193
134886
D297
I
L
G
H
I
I
Y
D
F
N
D
P
E
M
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38420
1188
135001
D296
I
L
E
H
I
C
Y
D
F
A
D
T
Q
M
M
Baker's Yeast
Sacchar. cerevisiae
P22138
1203
135723
S300
I
G
N
D
V
K
D
S
F
L
T
D
R
L
E
Red Bread Mold
Neurospora crassa
O74633
1234
138583
T298
Q
S
K
G
V
A
N
T
F
L
T
D
R
V
E
Conservation
Percent
Protein Identity:
100
99.5
98.6
N.A.
N.A.
89.6
85.2
N.A.
83.5
68.1
77
75.7
N.A.
45.2
47.1
28.3
N.A.
Protein Similarity:
100
99.8
99.5
N.A.
N.A.
95.4
90.3
N.A.
92.8
79.5
88.9
89.2
N.A.
64.9
66
44.9
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
86.6
80
N.A.
66.6
0
60
60
N.A.
26.6
20
20
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
93.3
N.A.
86.6
13.3
86.6
86.6
N.A.
53.3
40
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
42.4
44
Protein Similarity:
N.A.
N.A.
N.A.
42.8
61.9
60.7
P-Site Identity:
N.A.
N.A.
N.A.
13.3
33.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
20
46.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
0
7
0
0
0
7
0
0
0
0
0
% A
% Cys:
0
0
0
7
0
7
0
7
0
7
0
0
34
0
0
% C
% Asp:
0
7
0
7
0
40
54
14
0
0
14
20
0
0
7
% D
% Glu:
0
0
7
0
67
14
0
0
0
0
0
0
7
0
14
% E
% Phe:
0
0
7
0
7
0
0
0
80
14
0
0
0
0
0
% F
% Gly:
0
7
74
7
0
0
0
0
0
0
0
7
0
0
0
% G
% His:
0
0
0
14
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
74
0
0
7
14
7
0
0
7
0
7
0
0
7
0
% I
% Lys:
0
54
7
40
0
7
7
0
0
0
27
0
0
0
0
% K
% Leu:
0
14
0
0
0
0
0
7
0
34
0
0
7
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
14
% M
% Asn:
0
0
7
0
0
7
27
0
0
7
0
40
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% P
% Gln:
7
7
0
0
0
0
0
7
0
0
0
0
7
0
7
% Q
% Arg:
0
0
0
14
0
0
0
0
0
0
34
0
14
0
0
% R
% Ser:
0
7
0
0
0
7
0
60
0
0
0
14
34
0
47
% S
% Thr:
7
0
0
0
0
0
0
7
0
0
14
7
0
7
7
% T
% Val:
7
0
0
0
14
0
0
0
0
0
7
0
0
60
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
7
14
0
14
34
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _