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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CAB39L All Species: 37.88
Human Site: T246 Identified Species: 75.76
UniProt: Q9H9S4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H9S4 NP_001073138.1 337 39088 T246 R H N F A I M T K Y I S K P E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001102047 334 38678 T243 R H N F A I M T K Y I S K P E
Dog Lupus familis XP_542560 330 37728 T246 R H N F A I M T K Y I S K P E
Cat Felis silvestris
Mouse Mus musculus Q9DB16 337 39087 T246 R H N F T I M T K Y I S K P E
Rat Rattus norvegicus NP_001011917 337 39073 T246 R H N F T I M T K Y I S K P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001083396 337 39165 T246 R H N F S I M T K Y I S K P E
Zebra Danio Brachydanio rerio NP_001007328 334 38788 T243 R H N F T V M T R Y I S K P E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91891 339 39367 T247 R H N F T V M T R Y I S E P E
Honey Bee Apis mellifera XP_393376 338 39432 T246 R H N F T V M T R Y I S N P D
Nematode Worm Caenorhab. elegans O18211 338 39413 N250 R H N F S T M N K Y I T S P E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FGK3 343 39439 T252 R S N S A V M T K Y V S S R D
Baker's Yeast Sacchar. cerevisiae P32464 399 45835 N268 R S N N A L M N I Y I N S P E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.5 89.6 N.A. 98.5 97 N.A. N.A. N.A. 87.5 80.7 N.A. 64.3 66.2 57 N.A.
Protein Similarity: 100 N.A. 98.8 93.4 N.A. 99.1 98.2 N.A. N.A. N.A. 94.9 89.9 N.A. 81.7 81.6 74.8 N.A.
P-Site Identity: 100 N.A. 100 100 N.A. 93.3 93.3 N.A. N.A. N.A. 93.3 80 N.A. 73.3 66.6 66.6 N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 93.3 93.3 N.A. N.A. N.A. 100 93.3 N.A. 93.3 86.6 80 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 43.1 30 N.A.
Protein Similarity: N.A. N.A. N.A. 66.4 48.8 N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 42 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 84 % E
% Phe: 0 0 0 84 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 84 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 50 0 0 9 0 92 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 67 0 0 0 59 0 0 % K
% Leu: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 100 9 0 0 0 17 0 0 0 9 9 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 92 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 100 0 0 0 0 0 0 0 25 0 0 0 0 9 0 % R
% Ser: 0 17 0 9 17 0 0 0 0 0 0 84 25 0 0 % S
% Thr: 0 0 0 0 42 9 0 84 0 0 0 9 0 0 0 % T
% Val: 0 0 0 0 0 34 0 0 0 0 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _