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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC61A2
All Species:
63.33
Human Site:
Y173
Identified Species:
99.52
UniProt:
Q9H9S3
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9S3
NP_001136099.1
476
52248
Y173
D
E
L
L
Q
K
G
Y
G
L
G
S
G
I
S
Chimpanzee
Pan troglodytes
XP_507657
551
59257
Y248
D
E
L
L
Q
K
G
Y
G
L
G
S
G
I
S
Rhesus Macaque
Macaca mulatta
XP_001085071
1486
164008
Y1183
D
E
L
L
Q
K
G
Y
G
L
G
S
G
I
S
Dog
Lupus familis
XP_535191
551
60482
Y248
D
E
L
L
Q
K
G
Y
G
L
G
S
G
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLR1
476
52229
Y173
D
E
L
L
Q
K
G
Y
G
L
G
S
G
I
S
Rat
Rattus norvegicus
P61621
476
52246
Y173
D
E
L
L
Q
K
G
Y
G
L
G
S
G
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515762
609
66529
Y306
D
E
L
L
Q
K
G
Y
G
L
G
S
G
I
S
Chicken
Gallus gallus
XP_424024
535
57647
Y232
D
E
L
L
Q
K
G
Y
G
L
G
S
G
I
S
Frog
Xenopus laevis
NP_001080244
476
52132
Y173
D
E
L
L
Q
K
G
Y
G
L
G
S
G
I
S
Zebra Danio
Brachydanio rerio
Q90ZM2
476
52279
Y173
D
E
L
L
Q
K
G
Y
G
L
G
S
G
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609034
476
52166
Y173
D
E
L
L
Q
K
G
Y
G
L
G
S
G
I
S
Honey Bee
Apis mellifera
XP_001120255
476
52370
Y173
D
E
L
L
Q
K
G
Y
G
L
G
S
G
I
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_802085
475
52232
Y172
D
E
L
L
Q
K
G
Y
G
L
G
S
G
I
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32915
480
52918
Y175
D
E
L
L
S
K
G
Y
G
L
G
S
G
I
S
Red Bread Mold
Neurospora crassa
Q870W0
476
52293
Y175
D
E
L
L
Q
K
G
Y
G
L
G
S
G
I
S
Conservation
Percent
Protein Identity:
100
86.3
32
86.3
N.A.
100
93.4
N.A.
77.8
88.5
93.4
94.5
N.A.
91.1
89.5
N.A.
89.5
Protein Similarity:
100
86.3
32
86.3
N.A.
100
97
N.A.
78.1
88.9
97.4
97.6
N.A.
96.4
96
N.A.
94.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
100
100
N.A.
100
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
100
100
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
54.7
64.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
72.2
79.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
93.3
100
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
93.3
100
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
100
0
100
0
100
0
100
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% I
% Lys:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
100
100
0
0
0
0
0
100
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
94
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
7
0
0
0
0
0
0
100
0
0
100
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _