KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NHEJ1
All Species:
2.42
Human Site:
T223
Identified Species:
8.89
UniProt:
Q9H9Q4
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Q4
NP_079058.1
299
33337
T223
D
L
Y
M
A
V
T
T
Q
E
V
Q
V
G
Q
Chimpanzee
Pan troglodytes
XP_001160321
299
33384
K223
N
L
Y
M
A
V
T
K
Q
E
V
Q
V
G
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_853192
346
37978
R270
S
L
Y
M
A
V
T
R
Q
E
I
Q
V
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q3KNJ2
295
32721
V221
L
Q
S
L
Y
V
A
V
T
K
Q
Q
I
Q
A
Rat
Rattus norvegicus
Q6AYI4
304
33866
K228
S
L
Y
V
A
V
T
K
Q
Q
V
Q
A
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422052
298
32851
L225
Q
L
Y
M
A
V
T
L
Q
E
A
K
Q
A
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NV18
309
34164
S222
A
L
Y
M
A
V
N
S
G
K
T
G
R
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
N.A.
70.8
N.A.
73.9
75.6
N.A.
N.A.
49.1
N.A.
35.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
N.A.
77.1
N.A.
81.9
81.9
N.A.
N.A.
61.8
N.A.
54.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
86.6
N.A.
73.3
N.A.
13.3
60
N.A.
N.A.
53.3
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
N.A.
80
N.A.
33.3
73.3
N.A.
N.A.
66.6
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
86
0
15
0
0
0
15
0
15
15
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
58
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
15
0
0
15
0
29
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
15
0
15
0
0
% I
% Lys:
0
0
0
0
0
0
0
29
0
29
0
15
0
15
0
% K
% Leu:
15
86
0
15
0
0
0
15
0
0
0
0
0
0
0
% L
% Met:
0
0
0
72
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
15
15
0
0
0
0
0
0
72
15
15
72
15
15
58
% Q
% Arg:
0
0
0
0
0
0
0
15
0
0
0
0
15
29
29
% R
% Ser:
29
0
15
0
0
0
0
15
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
72
15
15
0
15
0
0
0
0
% T
% Val:
0
0
0
15
0
100
0
15
0
0
43
0
43
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
86
0
15
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _