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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: L2HGDH All Species: 4.55
Human Site: Y102 Identified Species: 50
UniProt: Q9H9P8 Number Species: 2
    Phosphosite Substitution
    Charge Score: 0.5
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H9P8 NP_079160.1 463 50359 Y102 G V I H S G I Y Y K P E S L K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q91YP0 464 50880 Y103 G V I H S G I Y Y K P E S L K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9N4Z0 433 47883 D102 D L S Y E F F D K E K V P Y K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. N.A. N.A. 82.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 52.2 N.A.
Protein Similarity: 100 N.A. N.A. N.A. N.A. 90 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 68.6 N.A.
P-Site Identity: 100 N.A. N.A. N.A. N.A. 100 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 N.A. N.A. N.A. N.A. 100 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 34 0 0 0 0 0 0 34 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 34 0 0 0 0 34 0 67 0 0 0 % E
% Phe: 0 0 0 0 0 34 34 0 0 0 0 0 0 0 0 % F
% Gly: 67 0 0 0 0 67 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 67 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 67 0 0 0 67 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 34 67 34 0 0 0 100 % K
% Leu: 0 34 0 0 0 0 0 0 0 0 0 0 0 67 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 67 0 34 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 34 0 67 0 0 0 0 0 0 0 67 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 67 0 0 0 0 0 0 0 0 0 34 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 34 0 0 0 67 67 0 0 0 0 34 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _