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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISG20L2
All Species:
8.79
Human Site:
S145
Identified Species:
17.58
UniProt:
Q9H9L3
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9L3
NP_112242.1
353
39154
S145
K
K
S
S
Q
K
K
S
S
K
K
N
H
P
Q
Chimpanzee
Pan troglodytes
XP_513892
352
39007
S145
K
S
S
Q
K
K
S
S
K
K
N
H
P
Q
K
Rhesus Macaque
Macaca mulatta
XP_001116730
354
39402
S146
K
K
G
S
Q
K
K
S
S
K
K
N
H
P
Q
Dog
Lupus familis
XP_547530
348
38717
G140
P
T
R
P
H
K
K
G
P
Q
K
N
P
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q3U1G5
368
41001
K145
K
K
K
S
L
K
K
K
I
A
T
E
N
S
T
Rat
Rattus norvegicus
Q6AXU3
369
41292
K144
K
G
S
K
K
P
L
K
K
K
I
A
T
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505322
104
11917
Chicken
Gallus gallus
XP_001232173
293
32909
H94
K
K
R
A
P
K
G
H
R
E
Q
K
K
P
L
Frog
Xenopus laevis
Q91560
421
46679
V147
A
A
E
K
S
D
E
V
S
K
G
K
K
R
K
Zebra Danio
Brachydanio rerio
NP_001096663
321
36753
L121
A
N
I
S
Q
R
D
L
T
Q
R
M
A
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08237
289
32876
A90
F
E
F
N
P
N
K
A
N
T
S
T
T
I
K
Red Bread Mold
Neurospora crassa
Q7S9B7
406
43643
S170
H
S
S
S
S
P
K
S
N
K
N
G
L
P
L
Conservation
Percent
Protein Identity:
100
99.7
97.1
86.4
N.A.
72.8
72.9
N.A.
21.2
48.4
23.7
42.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
97.7
89.8
N.A.
81.2
81.3
N.A.
24.9
59.7
40.8
58.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
33.3
93.3
33.3
N.A.
33.3
20
N.A.
0
26.6
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
53.3
93.3
40
N.A.
40
26.6
N.A.
0
46.6
26.6
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.9
27.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.2
42.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
40
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
0
9
0
0
0
9
0
9
0
9
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
9
0
0
0
9
0
0
9
0
9
0
9
0
% E
% Phe:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
9
0
0
0
9
9
0
0
9
9
0
0
0
% G
% His:
9
0
0
0
9
0
0
9
0
0
0
9
17
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
9
0
9
0
0
9
0
% I
% Lys:
50
34
9
17
17
50
50
17
17
50
25
17
17
0
25
% K
% Leu:
0
0
0
0
9
0
9
9
0
0
0
0
9
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
9
0
9
0
9
0
0
17
0
17
25
9
0
9
% N
% Pro:
9
0
0
9
17
17
0
0
9
0
0
0
17
34
9
% P
% Gln:
0
0
0
9
25
0
0
0
0
17
9
0
0
9
25
% Q
% Arg:
0
0
17
0
0
9
0
0
9
0
9
0
0
9
0
% R
% Ser:
0
17
34
42
17
0
9
34
25
0
9
0
0
9
0
% S
% Thr:
0
9
0
0
0
0
0
0
9
9
9
9
17
9
9
% T
% Val:
0
0
0
0
0
0
0
9
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _