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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ISG20L2 All Species: 17.58
Human Site: S111 Identified Species: 35.15
UniProt: Q9H9L3 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H9L3 NP_112242.1 353 39154 S111 A P S K K A D S V A A K V D L
Chimpanzee Pan troglodytes XP_513892 352 39007 S111 A P S K K A D S V A A K V D L
Rhesus Macaque Macaca mulatta XP_001116730 354 39402 S112 A P S K K A D S V A A K V D L
Dog Lupus familis XP_547530 348 38717 S106 P W L T P A P S Q K A G S A L
Cat Felis silvestris
Mouse Mus musculus Q3U1G5 368 41001 S111 A P S K K T A S V V S K I D L
Rat Rattus norvegicus Q6AXU3 369 41292 T110 T P A P S K K T D S V V A K I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505322 104 11917
Chicken Gallus gallus XP_001232173 293 32909 R60 G G G C P R K R G G R G R R K
Frog Xenopus laevis Q91560 421 46679 H113 S V P Q K S G H K I N G G I T
Zebra Danio Brachydanio rerio NP_001096663 321 36753 Y87 F F P K F T S Y L P N S T Y E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08237 289 32876 G56 A P R K R K N G S K I M D M V
Red Bread Mold Neurospora crassa Q7S9B7 406 43643 S136 L G L R G T S S S S S S S H I
Conservation
Percent
Protein Identity: 100 99.7 97.1 86.4 N.A. 72.8 72.9 N.A. 21.2 48.4 23.7 42.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 97.7 89.8 N.A. 81.2 81.3 N.A. 24.9 59.7 40.8 58.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 26.6 N.A. 66.6 6.6 N.A. 0 0 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 26.6 N.A. 80 33.3 N.A. 0 0 26.6 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.9 27.5
Protein Similarity: N.A. N.A. N.A. N.A. 51.2 42.1
P-Site Identity: N.A. N.A. N.A. N.A. 20 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 40 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 42 0 9 0 0 34 9 0 0 25 34 0 9 9 0 % A
% Cys: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 25 0 9 0 0 0 9 34 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % E
% Phe: 9 9 0 0 9 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 17 9 0 9 0 9 9 9 9 0 25 9 0 0 % G
% His: 0 0 0 0 0 0 0 9 0 0 0 0 0 9 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 9 9 0 9 9 17 % I
% Lys: 0 0 0 50 42 17 17 0 9 17 0 34 0 9 9 % K
% Leu: 9 0 17 0 0 0 0 0 9 0 0 0 0 0 42 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 9 0 9 0 % M
% Asn: 0 0 0 0 0 0 9 0 0 0 17 0 0 0 0 % N
% Pro: 9 50 17 9 17 0 9 0 0 9 0 0 0 0 0 % P
% Gln: 0 0 0 9 0 0 0 0 9 0 0 0 0 0 0 % Q
% Arg: 0 0 9 9 9 9 0 9 0 0 9 0 9 9 0 % R
% Ser: 9 0 34 0 9 9 17 50 17 17 17 17 17 0 0 % S
% Thr: 9 0 0 9 0 25 0 9 0 0 0 0 9 0 9 % T
% Val: 0 9 0 0 0 0 0 0 34 9 9 9 25 0 9 % V
% Trp: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 9 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _