KinATLAS
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DrugKiNET
KiNET-AM
Kinector
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTR5
All Species:
10.61
Human Site:
T393
Identified Species:
17.95
UniProt:
Q9H9F9
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9F9
NP_079131.3
607
68297
T393
V
V
D
S
K
P
E
T
P
D
L
E
Q
L
E
Chimpanzee
Pan troglodytes
XP_001145158
607
68237
T393
V
V
D
S
K
P
E
T
P
D
L
E
Q
L
E
Rhesus Macaque
Macaca mulatta
XP_001089026
607
68253
T393
V
V
D
S
K
P
E
T
P
D
L
E
Q
L
E
Dog
Lupus familis
XP_534418
363
41163
G160
L
L
Q
L
K
Y
P
G
H
L
A
A
I
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80US4
605
67941
P394
V
D
S
K
P
E
T
P
D
L
E
P
L
E
P
Rat
Rattus norvegicus
NP_001102070
330
37120
C127
L
G
V
S
S
Q
G
C
V
D
H
P
I
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515798
283
31357
E80
L
G
S
E
Q
S
L
E
D
V
E
N
I
N
D
Chicken
Gallus gallus
Q5ZJA4
611
69335
D397
D
S
K
P
E
T
P
D
L
D
P
L
S
S
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998653
592
66401
H372
L
S
L
S
L
Q
Q
H
R
L
L
R
A
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEC3
648
75103
P381
R
L
N
K
M
P
K
P
P
E
G
M
S
Q
A
Honey Bee
Apis mellifera
XP_623919
674
77387
K463
D
E
D
W
D
V
Y
K
V
I
N
R
E
G
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784230
560
63388
S355
S
D
G
S
Q
K
K
S
L
K
A
L
G
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q940Z2
590
67861
F373
R
L
L
T
T
A
A
F
D
R
G
K
G
E
D
Baker's Yeast
Sacchar. cerevisiae
P53946
755
87542
E378
L
K
K
A
Q
M
V
E
A
E
D
D
S
H
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.5
56.6
N.A.
88.8
50.5
N.A.
34.9
78.7
N.A.
56.5
N.A.
28.8
41.5
N.A.
41.8
Protein Similarity:
100
100
99.1
58.6
N.A.
94
51.7
N.A.
40.8
86.5
N.A.
73.4
N.A.
49
59.5
N.A.
61.7
P-Site Identity:
100
100
100
6.6
N.A.
6.6
13.3
N.A.
0
13.3
N.A.
13.3
N.A.
13.3
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
20
N.A.
6.6
26.6
N.A.
20
20
N.A.
26.6
N.A.
40
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
25
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.2
42.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
8
0
8
0
15
8
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
15
15
29
0
8
0
0
8
22
36
8
8
0
0
15
% D
% Glu:
0
8
0
8
8
8
22
15
0
15
15
22
8
22
29
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
15
8
0
0
0
8
8
0
0
15
0
15
8
8
% G
% His:
0
0
0
0
0
0
0
8
8
0
8
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
0
22
0
0
% I
% Lys:
0
8
15
15
29
8
15
8
0
8
0
8
0
0
0
% K
% Leu:
36
22
15
8
8
0
8
0
15
22
29
15
8
29
22
% L
% Met:
0
0
0
0
8
8
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
8
8
0
8
8
% N
% Pro:
0
0
0
8
8
29
15
15
29
0
8
15
0
0
8
% P
% Gln:
0
0
8
0
22
15
8
0
0
0
0
0
22
8
0
% Q
% Arg:
15
0
0
0
0
0
0
0
8
8
0
15
0
0
0
% R
% Ser:
8
15
15
43
8
8
0
8
0
0
0
0
22
8
0
% S
% Thr:
0
0
0
8
8
8
8
22
0
0
0
0
0
8
8
% T
% Val:
29
22
8
0
0
8
8
0
15
8
0
0
0
8
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _